The National Institutes of Health (NIH), through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), is inviting applications for the R21 exploratory/developmental research grants focused on pilot studies investigating biological, behavioral, and social mechanisms contributing to HIV pathogenesis. This funding opportunity aims to support innovative research aligned with NIH HIV/AIDS priorities, particularly addressing comorbidities and complications related to HIV, as well as the social determinants affecting health outcomes for individuals living with HIV. Eligible applicants include a wide range of institutions, such as higher education institutions, tribal governments, and community-based organizations, with a total budget limit of $275,000 available over a two-year project period. Interested parties should note that the application deadline is May 7, 2024, and further inquiries can be directed to NIH Grants Information at grantsinfo@nih.gov.