The National Institutes of Health (NIH) has announced a funding opportunity titled "Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)" aimed at supporting research initiatives that enhance health outcomes in Native American communities. This grant opportunity focuses on developing, adapting, and testing culturally appropriate health promotion and disease prevention interventions, with an emphasis on collaboration with tribal partners to ensure the research is both culturally relevant and scientifically rigorous. The initiative seeks to address significant health disparities faced by Native American populations by fostering local research capacities and developing scalable interventions that align with community values. Grants of up to $450,000 are available over a three-year period, with applications due by January 7, 2027. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-23-285.html.