The National Institutes of Health (NIH) has announced a funding opportunity titled "Intervention Research to Improve Native American Health," aimed at supporting research initiatives that enhance health outcomes in Native American populations. This initiative seeks proposals for R34 Planning Grants that focus on developing and testing culturally appropriate health interventions through community engagement, addressing critical health issues such as substance use, chronic diseases, and mental health disparities. Eligible organizations can request up to $450,000 over three years to conduct research that incorporates Indigenous Knowledge and cultural relevance, with an emphasis on preparing for future clinical trials. Interested applicants should note that the application deadline is January 7, 2027, and can find more information by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-378.html.