The National Institutes of Health (NIH) has announced a funding opportunity titled "NIAID, NIDDK, NIDA, and NIAAA Research Opportunities for New and 'At-Risk' Investigators (R01 Clinical Trial Optional)" aimed at supporting research projects in health-related fields. This initiative specifically targets New Investigators who have not previously secured substantial NIH funding and 'At-Risk' Investigators who may lose their funding, encouraging applications from diverse backgrounds to promote equity in the scientific workforce. The program is crucial for addressing health disparities through innovative research in areas such as infectious diseases, diabetes, drug abuse, and alcohol use. Applications will be accepted starting January 5, 2025, with a maximum project period of five years, and interested applicants can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. The opportunity does not require cost-sharing or matching and is categorized under discretionary funding with a CFDA number of 93.855.