The National Institutes of Health (NIH) is offering the AIDS-Science Track Award for Research Transition (A-START), a federal grant aimed at facilitating the entry of early-stage investigators into research that integrates substance use disorders (SUD) with HIV/AIDS. This funding opportunity encourages applications for Small Research Grant (R03) projects that can be completed within two years, with budgets up to $100,000 annually, focusing on critical areas such as epidemiology, intervention strategies, and health disparities affecting substance users. The total funding available for this initiative is approximately $1,000,000, with an estimated 12 awards anticipated for fiscal year 2022. Interested applicants must submit their proposals by January 7 each year and can reach out to the NIH OER Webmaster at OERWebmaster03@od.nih.gov for further inquiries or guidance.