The National Institutes of Health (NIH) is planning to publish a funding opportunity announcement for the BRAIN Initiative. This initiative aims to support the development and preclinical testing of next-generation recording and/or modulation devices for human use. The goal is to enhance our understanding of the human central nervous system and improve the treatment of nervous system disorders. The funding opportunity will utilize the R18 activity code and is expected to be published in January 2024, with an anticipated application receipt date in May 2024. The estimated award date is February 12, 2025, and the estimated project start date is February 14, 2025. The maximum award ceiling for this grant is $750,000.