The National Institutes of Health (NIH) has announced a funding opportunity for the BRAIN Initiative, focusing on the engineering and optimization of molecular technologies for the functional dissection of neural circuits. This initiative aims to develop high-impact molecular tools that can monitor and manipulate neural cell activity, facilitating advancements in neuroscience research and the treatment of brain disorders. The funding, estimated at $13 million annually, will support 5 to 9 awards over a maximum project period of five years, with applications due by October 17, 2024. Interested applicants can find more information and contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-22-245.html.