BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
ID: 348769Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/348769

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-24-280.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity under the BRAIN Initiative, aimed at developing and validating novel tools to analyze cell-specific and circuit-specific processes in the brain. This initiative encourages innovative approaches to enhance the understanding of brain function, particularly through the creation of non-invasive methods for targeting specific brain cell types and advancing technologies for cellular analysis. With a total budget of approximately $8 million allocated for 6-9 awards, applicants must submit proposals that include a Plan for Enhancing Diverse Perspectives (PEDP) and adhere to strict submission guidelines. The application period begins in May 2024, with a project duration of up to three years, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-MH-24-280-Full-Announcement.html
    RFA-MH-24-280.html
    The Department of Health and Human Services released a Notice of Funding Opportunity (NOFO) under the BRAIN Initiative, aimed at advancing research on brain functions through innovative neurotechnologies. This initiative encourages the development and validation of novel tools that can analyze cell-specific and circuit-specific processes influencing brain activity. The funding opportunity is open to various applicants, including higher education institutions, non-profits, and small businesses, with a total budget of approximately $8 million for 6-9 awards. Key priorities include creating non-invasive methods for targeting specific brain cell types, advancing technologies for cellular analysis, and fostering diversity and inclusivity in research teams. Applicants must submit proposals that include a Plan for Enhancing Diverse Perspectives (PEDP) and adhere to strict submission guidelines. Applications will undergo peer review to assess scientific merit, innovation, approach, and the significance of the proposed research. The program symbolizes NIH's commitment to deepening understanding of the brain's complex operations and ultimately aims to improve treatments for brain disorders. The application deadlines commence in May 2024, with a project period extending up to three years.
    Similar Opportunities
    BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System," aimed at enhancing technologies for recording neural activity and addressing significant challenges in neuroscience research. This initiative seeks applications focused on optimizing existing or emerging technologies through iterative testing with end users, with the goal of improving network recording capabilities and developing tools for circuit manipulation that can be validated in vivo. The funding, anticipated at $10 million per year for 15-20 awards, requires applicants to include a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research, with submissions due by January 20, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative, titled "New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)." This initiative aims to support proof-of-concept testing and the development of innovative neurotechnologies that can enhance the understanding of brain circuit dynamics and facilitate transformative neuroscience research. The program encourages high-risk, high-impact projects that integrate diverse scientific domains and require applicants to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposals. The total estimated funding available is $10 million annually, with plans to support 15-20 awards over a maximum project period of three years. Interested applicants must adhere to strict submission guidelines, and the application deadline is January 20, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    BRAIN Initiative: Targeted BRAIN Circuits Planning Projects TargetedBCPP (R34 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "BRAIN Initiative: Targeted BRAIN Circuits Planning Projects" (RFA-NS-23-023), aimed at supporting exploratory research on neural circuits that influence behavior. This initiative seeks applications that establish the feasibility and validity necessary for subsequent larger projects, focusing on innovative, methodologically-integrated approaches to understanding circuit activity and mental experiences, while explicitly excluding clinical trials. The NIH plans to commit up to $2.5 million annually for approximately 10 awards, with each award allowing budgets of up to $450,000 over a two-year period. Interested applicants must submit their proposals by October 2, 2024, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Brain Behavior Quantification and Synchronization (R61/R33 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "BRAIN Initiative: Brain Behavior Quantification and Synchronization (R61/R33 Clinical Trial Optional)" aimed at developing and validating innovative tools to measure and synchronize human behaviors with brain activity. This initiative seeks to support a multidisciplinary approach, integrating fields such as neurobiology, engineering, and artificial intelligence, with a focus on creating tools that can accurately link behavioral data to brain activity. Approximately $10 million is available for funding, with an anticipated selection of 8-10 awards, and applications must adhere to specific guidelines, including a Plan for Enhancing Diverse Perspectives (PEDP) and neuroethics considerations. Interested applicants can find more information and submit inquiries via email to grantsinfo@nih.gov, with the application deadline set for January 22, 2025.
    BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative and Integrative Models of Behavior at the Organismal Level," aimed at advancing behavioral science through innovative research. This initiative seeks applications that focus on developing and validating tools for minimally invasive, high-resolution measurement of behavior, integrating multidimensional behavioral, neural, and environmental data, and creating new theoretical models to understand behavior as a complex dynamic system. With an anticipated funding commitment of approximately $8 million, the program emphasizes interdisciplinary collaboration and requires a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity. Interested applicants should submit their proposals by October 9, 2026, and can direct inquiries to grantsinfo@nih.gov for further information.
    BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative to support the development of innovative recording and modulation technologies for diagnosing and treating central nervous system (CNS) diseases. The initiative aims to advance technologies from proof of concept to readiness for first-in-human studies, encouraging diverse, team-based applications that integrate various domains of expertise. This funding opportunity, with an award ceiling of $750,000 and a total budget of approximately $8 million for 5-7 awards, requires applicants to submit a Plan for Enhancing Diverse Perspectives and several key attachments. Interested parties should note that the application submission period begins on April 29, 2024, and closes on January 28, 2027. For further details, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-031.html.
    BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R01 Clinical Trial Optional)" aimed at exploring the ethical dimensions of neuroscience research. This initiative encourages multidisciplinary teams to address core ethical issues such as informed consent, data privacy, and health disparities, emphasizing the importance of inclusive research practices. Funding is available for both exploratory projects under R21 and larger research grants under R01, with an anticipated budget of $3 million per year for up to eight awards. Interested applicants must submit their proposals by October 9, 2026, and are required to include a Plan for Enhancing Diverse Perspectives (PEDP) to integrate diverse viewpoints in their research. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)." This initiative aims to support research that develops and validates innovative tools for minimally invasive, high-resolution measurement of behavior in non-human animal models, while integrating multidimensional behavioral, neural, and environmental data to understand behavior as a complex dynamic system. The funding, which totals approximately $8 million for up to ten awards annually, emphasizes the importance of interdisciplinary collaboration and requires applicants to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposals. Interested applicants should note that the application deadline is October 9, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative for exploratory research using invasive neural recording and stimulating technologies in the human brain. This initiative aims to assemble diverse, multidisciplinary teams to investigate high-impact questions in human neuroscience, focusing on establishing feasibility and proof-of-principle for future invasive studies while addressing clinical and ethical considerations. The NIH plans to commit approximately $6 million to fund multiple awards, with each application budget capped at $700,000 for direct costs per year over a maximum project period of three years. Interested applicants can find more information and submit inquiries via email at grantsinfo@nih.gov, with the application deadline set for September 19, 2025.
    BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R21 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative for research on the ethical implications of advancements in neurotechnology and brain science, designated as R21 Clinical Trial Optional grants. This initiative invites multi-disciplinary teams to explore critical ethical issues related to brain research, including topics such as brain imaging, data privacy, and informed consent, with the aim of fostering diverse collaborations and addressing significant ethical challenges in the field. The total funding available is $2 million annually over three years, supporting up to eight new awards, with individual project budgets capped at $275,000 for a two-year period. Interested applicants should note that the application period opens on September 11, 2024, and closes on October 9, 2026; for further inquiries, they can contact NIH Grants Information at grantsinfo@nih.gov.