BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
ID: 348769Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity under the BRAIN Initiative, aimed at developing and validating novel tools to analyze cell-specific and circuit-specific processes in the brain. This initiative encourages innovative approaches to enhance the understanding of brain function, particularly through the creation of non-invasive methods for targeting specific brain cell types and advancing technologies for cellular analysis. With a total budget of approximately $8 million allocated for 6-9 awards, applicants must submit proposals that include a Plan for Enhancing Diverse Perspectives (PEDP) and adhere to strict submission guidelines. The application period begins in May 2024, with a project duration of up to three years, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    Files
    Title
    Posted
    The Department of Health and Human Services released a Notice of Funding Opportunity (NOFO) under the BRAIN Initiative, aimed at advancing research on brain functions through innovative neurotechnologies. This initiative encourages the development and validation of novel tools that can analyze cell-specific and circuit-specific processes influencing brain activity. The funding opportunity is open to various applicants, including higher education institutions, non-profits, and small businesses, with a total budget of approximately $8 million for 6-9 awards. Key priorities include creating non-invasive methods for targeting specific brain cell types, advancing technologies for cellular analysis, and fostering diversity and inclusivity in research teams. Applicants must submit proposals that include a Plan for Enhancing Diverse Perspectives (PEDP) and adhere to strict submission guidelines. Applications will undergo peer review to assess scientific merit, innovation, approach, and the significance of the proposed research. The program symbolizes NIH's commitment to deepening understanding of the brain's complex operations and ultimately aims to improve treatments for brain disorders. The application deadlines commence in May 2024, with a project period extending up to three years.
    Similar Opportunities
    BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative aimed at developing and validating novel tools to analyze cell-specific and circuit-specific processes in the brain. This initiative encourages interdisciplinary collaboration to enhance the understanding of complex neural circuits, focusing on the creation of innovative, high-precision techniques that can be applied across various species. Approximately $8 million will be allocated to support 6-9 awards, with applications due by February 9, 2027. Interested applicants must submit a Plan for Enhancing Diverse Perspectives and adhere to NIH policies throughout the application process; for further details, contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-170.html.
    BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System," aimed at enhancing technologies for recording neural activity and addressing significant challenges in neuroscience research. This initiative seeks applications focused on optimizing existing or emerging technologies through iterative testing with end users, with the goal of improving network recording capabilities and developing tools for circuit manipulation that can be validated in vivo. The funding, anticipated at $10 million per year for 15-20 awards, requires applicants to include a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research, with submissions due by January 20, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative, titled "New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)." This initiative aims to support proof-of-concept testing and the development of innovative neurotechnologies that can enhance the understanding of brain circuit dynamics and facilitate transformative neuroscience research. The program encourages high-risk, high-impact projects that integrate diverse scientific domains and require applicants to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposals. The total estimated funding available is $10 million annually, with plans to support 15-20 awards over a maximum project period of three years. Interested applicants must adhere to strict submission guidelines, and the application deadline is January 20, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System," aimed at advancing neuroscience research through innovative technology development. This initiative seeks applications for the creation of new hardware, software, or molecular constructs that address challenges in recording and modulating neural cells and circuits, with a focus on high-risk projects that could lead to transformative outcomes in understanding dynamic signaling within the central nervous system. The program allocates an estimated $10 million annually for 15-20 awards, emphasizing collaboration across scientific domains and encouraging participation from diverse institutions, particularly those supporting early-career researchers and underserved populations. Interested applicants should note that the application submission deadlines begin on May 2, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for clinical studies aimed at advancing next-generation devices for recording and modulation in the human central nervous system, under the BRAIN Initiative. This initiative seeks to support small clinical trials that provide critical data necessary for the development of devices intended to treat central nervous system disorders, particularly those requiring an Investigational Device Exemption (IDE) from the FDA. The funding is crucial for enhancing neurotechnology and improving treatment outcomes, with NIH planning to allocate approximately $10 million annually for 5 to 7 awards, each with a maximum budget of $1.5 million per year for up to five years. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with applications due by September 28, 2026.
    BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative and Integrative Models of Behavior at the Organismal Level," aimed at advancing behavioral science through innovative research. This initiative seeks applications that focus on developing and validating tools for minimally invasive, high-resolution measurement of behavior, integrating multidimensional behavioral, neural, and environmental data, and creating new theoretical models to understand behavior as a complex dynamic system. With an anticipated funding commitment of approximately $8 million, the program emphasizes interdisciplinary collaboration and requires a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity. Interested applicants should submit their proposals by October 9, 2026, and can direct inquiries to grantsinfo@nih.gov for further information.
    BRAIN Initiative: Brain Behavior Quantification and Synchronization (R61/R33 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "BRAIN Initiative: Brain Behavior Quantification and Synchronization (R61/R33 Clinical Trial Optional)" aimed at developing and validating innovative tools to measure and synchronize human behaviors with brain activity. This initiative seeks to support a multidisciplinary approach, integrating fields such as neurobiology, engineering, and artificial intelligence, with a focus on creating tools that can accurately link behavioral data to brain activity. Approximately $10 million is available for funding, with an anticipated selection of 8-10 awards, and applications must adhere to specific guidelines, including a Plan for Enhancing Diverse Perspectives (PEDP) and neuroethics considerations. Interested applicants can find more information and submit inquiries via email to grantsinfo@nih.gov, with the application deadline set for January 22, 2025.
    BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative to support the development of innovative recording and modulation technologies for diagnosing and treating central nervous system (CNS) diseases. The initiative aims to advance technologies from proof of concept to readiness for first-in-human studies, encouraging diverse, team-based applications that integrate various domains of expertise. This funding opportunity, with an award ceiling of $750,000 and a total budget of approximately $8 million for 5-7 awards, requires applicants to submit a Plan for Enhancing Diverse Perspectives and several key attachments. Interested parties should note that the application submission period begins on April 29, 2024, and closes on January 28, 2027. For further details, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-031.html.
    BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R01 Clinical Trial Optional)" aimed at exploring the ethical dimensions of neuroscience research. This initiative encourages multidisciplinary teams to address core ethical issues such as informed consent, data privacy, and health disparities, emphasizing the importance of inclusive research practices. Funding is available for both exploratory projects under R21 and larger research grants under R01, with an anticipated budget of $3 million per year for up to eight awards. Interested applicants must submit their proposals by October 9, 2026, and are required to include a Plan for Enhancing Diverse Perspectives (PEDP) to integrate diverse viewpoints in their research. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)." This initiative aims to support research that develops and validates innovative tools for minimally invasive, high-resolution measurement of behavior in non-human animal models, while integrating multidimensional behavioral, neural, and environmental data to understand behavior as a complex dynamic system. The funding, which totals approximately $8 million for up to ten awards annually, emphasizes the importance of interdisciplinary collaboration and requires applicants to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposals. Interested applicants should note that the application deadline is October 9, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.