Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)
ID: 354996Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/354996

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-238.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)" aimed at supporting innovative mechanistic research to develop precision probiotic interventions. This initiative utilizes a biphasic award mechanism, comprising an R61 phase focused on identifying host biological patterns that correlate with probiotic responses, followed by an R33 phase that builds on these findings through rigorous mechanistic studies. The program emphasizes the importance of understanding variations in probiotic efficacy among individuals, influenced by factors such as genetics and microbiome composition, and requires applicants to include a Plan for Enhancing Diverse Perspectives (PEDP). Interested applicants should note that the application deadline is September 1, 2024, with a project period not exceeding five years. For further inquiries, contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-238-Full-Announcement.html
    PAR-24-238.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is offering a funding opportunity titled "Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)." This initiative aims to support innovative mechanistic research for developing precision probiotic interventions. It employs a biphasic award mechanism, divided into R61 and R33 phases. The R61 phase, lasting 1-2 years, focuses on identifying host biological patterns that correlate with probiotic responses. The R33 phase will build on the R61 findings to explore causal factors through rigorous mechanistic studies. Funding is available for applications that align with NIH's mission, emphasizing understanding variations in probiotic efficacy among individuals linked to factors like genetics and microbiome composition. A companion R33 funding opportunity is also available for projects not requiring the initial R61 phase. Concerns about diversity in research perspectives are emphasized, making a Plan for Enhancing Diverse Perspectives (PEDP) mandatory in applications. The application process is detailed, with specific requirements for project organization and milestones for advancing from R61 to R33. The deadline for application submission is September 01, 2024, with a project period not exceeding 5 years. This initiative reflects NIH's commitment to advancing precision medicine in probiotic therapy research.
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