The National Institutes of Health (NIH) is inviting applications for the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), aimed at addressing immunologic and physiological challenges in xenotransplantation. Applicants are required to propose at least two synergistic research projects that outline strategies to overcome barriers affecting the survival and function of xenografts, with a focus on preclinical studies involving organ transplants from genetically modified pigs to nonhuman primates or human decedents. This initiative is critical in the context of increasing organ transplant demands, as it seeks to mitigate risks such as immune rejection and zoonotic disease transmission. A total funding of $6.4 million is available for three to five cooperative agreement awards, with a maximum project duration of five years. Interested parties can find more information and submit inquiries via grantsinfo@nih.gov, and the application deadline is August 9, 2024.