The U.S. Agency for International Development (USAID) is inviting submissions for the Frontier Health Markets (FHM) Annual Program Statement (APS), aimed at enhancing global health outcomes, particularly in maternal and child health, HIV/AIDS control, and infectious disease management. Eligible applicants include U.S. and non-U.S. public, private, for-profit, and nonprofit organizations, as well as institutions of higher education and international organizations, who are encouraged to submit concept papers for potential funding under this initiative. This APS serves as an umbrella document for multiple awards and emphasizes the importance of engaging local health markets and the private sector to achieve U.S. Government health priorities. Interested parties can reach out to Jacquelin Bell at jacbell@usaid.gov for further inquiries, with the submission deadline for concept papers set for February 24, 2028.