The USAID Global Health Broad Agency Announcement (BAA) for Research and Development (2018) invites collaboration in creating innovative health solutions to address critical issues in developing countries. This BAA outlines a two-step process: the initial announcement and subsequent Addenda that detail funding opportunities. The goal is to engage various organizations in co-creating effective interventions addressing maternal and child health and combating preventable diseases like HIV/AIDS and malaria. Key elements include a framework for co-creation, co-design, and co-investment among partners. The document emphasizes the need for high-impact projects and stresses that proposals must demonstrate significant contributions toward global health improvements. Awards are granted based on criteria such as reputation, technical ability, and the project’s potential for scalability and sustainability. The BAA, effective until May 30, 2022, stipulates insights on eligibility, collaboration rights, award types (including grants and contracts), and the necessity of protecting intellectual property during proposal evaluation. This initiative reflects USAID's commitment to leveraging scientific advancements to diminish health disparities in developing nations rapidly.