The "Saving Lives at Birth" initiative, facilitated by USAID, aims to encourage innovative proposals to reduce maternal and neonatal mortality through a Broad Agency Announcement (BAA) and its Addendum. The program welcomes diverse organizations, including for-profit and non-profit entities, academic institutions, and civic groups, with specific eligibility requirements for applicants based on geographical focus and partnerships. Organizations can submit multiple proposals, and collaboration across disciplines is encouraged. The funding is categorized into seed, validation, and transition stages, with varying award amounts based on project scope—generally up to $250,000 for seed and validation projects and up to $2,000,000 for transitions to scale. The applications are restricted to an online submission process and a set timeline with no extensions. Successful applicants could begin implementation of their projects following the finalization of awards anticipated between September and December 2015. This program represents an important federal effort to leverage diverse expertise in tackling crucial health challenges in low-income and middle-income countries.