HEAL Initiative: HEAL KIDS (Knowledge, Innovation and Discovery Studies): Chronic Pain Program (UC2 Clinical Trial Optional)
ID: 355414Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $1M

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for the HEAL KIDS Chronic Pain Collaborating Research Teams Program, part of the HEAL Initiative aimed at addressing chronic pain in children and adolescents. This funding opportunity seeks interdisciplinary research projects that leverage clinical research, innovative technologies, and measurement science to enhance understanding and management of pediatric chronic pain conditions. The initiative emphasizes collaboration across various NIH institutes to explore the biopsychosocial aspects of pain, develop effective interventions, and promote diverse perspectives in research teams, particularly from underrepresented groups. Proposals can request up to $1.3 million per year for a project period of five years, with applications due by November 9, 2024. For further information, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-AR-24-007.html.

    Point(s) of Contact
    Files
    Title
    Posted
    The HEAL Initiative's National Institutes of Health (NIH) is inviting applications for the HEAL KIDS Chronic Pain Collaborating Research Teams Program, aimed at interdisciplinary research on chronic pain in children and adolescents. This funding opportunity encourages collaborations across various NIH institutes to investigate the biopsychosocial aspects of pediatric chronic pain, focusing on age-appropriate therapeutic strategies and innovative pain management. Proposals should address critical challenges, utilize advanced technologies, and promote diverse perspectives in research teams, including those from underrepresented groups. The initiative aims to understand pain mechanisms, identify risk factors, and develop effective interventions while considering the unique developmental issues in pediatric populations. Applications are due by November 9, 2024, and must include a Plan for Enhancing Diverse Perspectives, reflecting NIH’s commitment to inclusive research. The budget for proposals can reach up to $1.3 million per year, with a project period of five years. This funding opportunity emphasizes collaboration and aims to generate impactful research addressing pediatric pain, ultimately contributing to solutions for the ongoing opioid crisis.
    Similar Opportunities
    HEAL Initiative: Understanding Individual Differences in Human Pain Conditions (R01 - Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative aimed at understanding individual differences in human pain conditions through the R01 grant mechanism. This initiative seeks research proposals that focus on the holistic understanding of pain variability among individuals, emphasizing the collection of clinical and preclinical data to inform personalized pain management strategies. The program is particularly relevant in the context of addressing the ongoing opioid crisis and aims to foster innovative, evidence-based solutions for pain treatment by encouraging multidisciplinary approaches and patient engagement. Approximately $4 million is available to support 3-4 awards, with applications due by February 6, 2025. Interested applicants can find more information and application guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.
    HEAL Initiative: Understanding Individual Differences in Human Pain Conditions (R01 - Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative, aimed at understanding individual differences in human pain conditions through the R01 grant mechanism. This initiative seeks to support research that holistically examines inter-individual differences in pain experiences, focusing on personalized pain management strategies and the collection of clinical and preclinical data. The funding is particularly important for advancing knowledge on the biological and psychosocial factors influencing pain sensitivity and treatment responses, especially in underserved populations. NIH plans to allocate approximately $4 million for 3-4 awards, with each application eligible for up to $650,000 in direct costs over a five-year period. Interested applicants must submit their proposals by February 6, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the HEAL Initiative's funding opportunity titled "Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)." This initiative aims to support pilot projects that identify new druggable targets for pain by generating preliminary data on understudied proteins associated with pain management. The funding opportunity is particularly significant as it seeks to advance research in pain management and drug discovery, contributing to the broader goal of addressing the opioid addiction crisis. Eligible applicants can receive up to $100,000 for projects lasting one year, with applications due by July 16, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-24-197.html.
    HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity through the HEAL Initiative aimed at supporting research for non-opioid analgesics via the R61/R33 Exploratory/Developmental Phased Award. This initiative encourages applications that focus on the early translational steps in developing novel pain treatment strategies, including the development and validation of assays and the identification of potential therapeutic agents, while explicitly prohibiting clinical trials. The funding amount is up to $350,000 per year, with a total project period not exceeding three years, and applications are due by January 15, 2027. Interested applicants can find more information and application guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative aimed at discovering and validating novel therapeutic targets for safe and effective pain treatment through the R01 Clinical Trial Not Allowed grant. This initiative seeks proposals that focus on basic science research targeting the peripheral nervous system, central nervous system, and other tissues, with an emphasis on developing pain therapeutics that minimize side effects and addiction risks. The NIH plans to award 8-10 grants, with project durations of up to five years, addressing various pain conditions including acute and chronic pain syndromes, amidst the ongoing opioid crisis. Interested applicants must submit their proposals by December 6, 2024, and can find additional information and submission guidelines at the provided NIH link or contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov.
    HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative to support the development of non-addictive analgesic therapeutics, specifically small molecules and biologics, aimed at treating pain. The initiative seeks to accelerate the optimization and transition of promising therapeutic candidates to Phase I clinical trials, requiring applicants to demonstrate a compelling biological rationale and suitable assays for their projects. This funding is crucial for addressing the needs of over 25 million Americans suffering from chronic pain while providing alternatives to opioids. Approximately $11 million is anticipated for distribution across four awards in FY 2024, with applications due by January 24, 2024. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative, titled "Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)." This initiative aims to support early-stage translational research focused on developing and validating tests for non-opioid analgesics, including small molecules and biologics, to address the ongoing opioid crisis and improve pain management. The program anticipates a funding pool of $2.5 million, with plans to award approximately 4-5 grants in FY 2025, and applications are due by January 15, 2027. Interested applicants can find more information and application details at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.
    HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management," aimed at addressing the national opioid public health crisis. This initiative encourages small businesses to develop innovative, non-addictive therapies and technologies for improved pain management, including new medications, pain-assessment devices, and treatment strategies for chronic pain. The funding available includes up to $275,766 for Phase I and $1,838,436 for Phase II grants, with applications due by April 4, 2025. Interested applicants can find more information and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.
    NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Patient-Oriented Research Career Development award (K23 - Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the HEAL Initiative PainCare Clinician Training Program (PCTP), a Mentored Patient-Oriented Research Career Development award (K23), aimed at supporting early-career clinician-scientists in conducting patient-oriented research in pain management. This grant program is designed to cultivate a new cohort of independent researchers capable of leading clinical trials that address chronic pain, a significant health issue affecting over 25 million Americans. Awardees will receive salary support, research expenses, and training in rigorous research methodologies, while also engaging with established mentoring teams and participating in annual networking meetings. The application deadline is July 12, 2027, and interested applicants can find more information and contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-24-220.html.
    HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the HEAL Initiative: Pain Research Enhancement Program (PREP), a federal grant aimed at supporting pain research projects from R15-eligible institutions. This initiative seeks to promote rigorous basic and mechanistic pain research, foster interdisciplinary collaborations, and enhance the research environment for health professional trainees and students. The program is crucial for diversifying the pain research workforce and advancing understanding of pain mechanisms, with funding available up to $375,000 over a maximum three-year period. Applications will be accepted starting October 18, 2024, with a deadline of November 19, 2024, and interested applicants can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.