Organs-on-a-Chip in Dental, Oral, and Craniofacial Research (DOC-OoCs) (R21 Clinical Trial Not Allowed)
ID: 356376Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $275K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356376

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DE-25-002.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering an R21 exploratory/developmental grant aimed at funding innovative research in the development of organ-on-a-chip (OoC) models for dental, oral, and craniofacial (DOC) applications. The primary objective is to validate these microfluidic systems for disease modeling and pre-clinical efficacy studies, promoting a multidisciplinary approach that integrates fields such as bioengineering and computational biology. This initiative is crucial for enhancing drug testing and improving preclinical models, ultimately leading to better clinical trial designs and reducing reliance on animal testing. The total funding available for FY 2025 is $1 million, with individual awards capped at $275,000 over two years. Applications are due by November 19, 2024, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DE-25-002-Full-Announcement.html
    RFA-DE-25-002.html
    The National Institutes of Health (NIH) is offering an R21 exploratory/developmental grant to fund interdisciplinary research aimed at developing organ-on-a-chip (OoC) models specifically for dental, oral, and craniofacial (DOC) applications. The program encourages projects that validate these microfluidic systems for disease modeling and pre-clinical studies, emphasizing the need for a multidisciplinary approach that integrates various fields, such as bioengineering and computational biology. The total funding available for FY 2025 is $1 million to support 3-4 awards, with a budget limit of $275,000 for each applicant over two years. Eligible applicants include a wide range of organizations, from higher education institutions to for-profit and nonprofit entities. Applications are due by November 20, 2024, with reviews anticipated in early 2025. The overall goal is to utilize OoCs to enhance drug testing and improve preclinical models, ultimately leading to better clinical trial design and reduced reliance on animal testing. Key considerations for eligibility and application submission are outlined, with specific emphasis placed on innovative approaches and the expected impact on DOC research.
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