The National Institutes of Health (NIH) is offering research grants aimed at analyzing existing genomic data related to human dental, oral, and craniofacial (DOC) health through the NIDCR Research Grants program. Funded projects will utilize statistical and computational methods to address significant biomedical questions in DOC biology, particularly prioritizing studies that explore oral health disparities and the pathogenesis of genetic variants. Applications must employ or develop innovative data analysis methods, potentially including AI and machine learning, and experimental validation is required. Notably, the funding opportunity encourages the use of publicly available genomic datasets for research while adhering to the NIH's data sharing policy. The application process requires adherence to specific guidelines, including compliance with existing registrations in various federal systems, and focuses on rigorous criteria for merit review. Eligible applicants include higher education institutions and nonprofits, among others, with an emphasis on diversity and inclusion. The application due dates and scopes are outlined, with projects lasting up to three years contingent on NIH appropriations. This funding notice reflects ongoing efforts to enhance research quality and accessibility in the dental and craniofacial fields by leveraging existing data resources.