The National Institutes of Health (NIH) is preparing to release a Notice of Funding Opportunity (NOFO) aimed at supporting observational studies focused on biomarkers of cognitive decline and dementias of aging in individuals on the Autism Spectrum. The primary objective of this initiative is to investigate age-related neurodegeneration within the Autism Spectrum Disorders (ASD) population, characterize the physiopathology of Alzheimer's disease and related dementias, and develop precision-medicine strategies tailored to this unique group. This funding opportunity encourages collaborations between researchers specializing in autism and those with expertise in aging and dementia, fostering interdisciplinary approaches to address this critical area of health research. Interested applicants can reach out to Dr. Alessandra Rovescalli at rovescaa@mail.nih.gov or by phone at 301-215-0335 for further information, with the estimated synopsis posting date set for December 1, 2025, and applications expected to be solicited by February 5, 2026.