The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) titled "Novel Approaches to Advance Precision Aging and Cognitive Health," aimed at soliciting applications that leverage innovative study designs and methods, including machine learning and artificial intelligence, to enhance cognitive health in older adults. This initiative seeks to develop personalized prevention plans and interventions by discovering health and function profiles at the individual level, encompassing research from cellular to societal levels. The grant will utilize the R01 activity code, with applications not currently being solicited; however, potential applicants are encouraged to begin forming collaborations and project ideas in anticipation of the funding opportunity. For further inquiries, interested parties may contact Dr. Molly Wagster at wagsterm@nia.nih.gov or by phone at 301-496-9350. The estimated synopsis post date is August 6, 2026, with a close date of October 6, 2026, and an anticipated award date of July 6, 2027.