12258238 -Synopsis/Solicitation for Bayesian precision dosing software system
ID: 12258238Type: Solicitation
Overview

Buyer

DEPT OF DEFENSEDEFENSE HEALTH AGENCY (DHA)DEFENSE HEALTH AGENCYFALLS CHURCH, VA, 22042, USA

NAICS

Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518210)

PSC

IT AND TELECOM - BUSINESS APPLICATION/APPLICATION DEVELOPMENT SOFTWARE AS A SERVICE (DA10)

Set Aside

Total Small Business Set-Aside (FAR 19.5) (SBA)

Original Source

https://sam.gov/opp/b85bef2068f64662935109cb9edf3230/view
Timeline
    Description

    The Defense Health Agency (DHA) is soliciting proposals for a Bayesian precision dosing software system to be utilized at the Walter Reed National Military Medical Center (WRNMMC). This software aims to enhance patient-specific vancomycin therapy by predicting future area-under-curve (AUC) or serum levels and assessing toxicity probabilities, thereby improving therapeutic efficacy while minimizing nephrotoxicity for critical care patients. The project will be structured as a software as a service (SaaS) deployment, ensuring HIPAA compliance and providing extensive training for clinical staff, with a contract period spanning from June 2025 to May 2030. Interested vendors must submit their proposals by May 23, 2025, and can contact Cinthia Funes at cinthia.g.funes.civ@health.mil for further information.

    Point(s) of Contact
    Cinthia Funes
    cinthia.g.funes.civ@health.mil
    Erica S. Oh
    erica.s.oh.civ@health.mil
    Files
    Title
    Posted
    55- Solicitation 12258238 PWS.docx
    The Defense Health Agency seeks to develop a cloud-based Bayesian algorithm for precise dosing of vancomycin at Walter Reed National Military Medical Center (WRNMMC). This initiative aims to improve patient-specific vancomycin therapy, aligning with 2020 IDSA/ASHP guidelines, by facilitating Area Under the Curve (AUC)-based pharmacokinetic modeling. The tool is designed to enhance therapeutic efficacy while minimizing nephrotoxicity, particularly for critical care patients. Key functionalities will include real-time pharmacokinetic advisories, customized dosing regimens, toxicity assessment, and integrated reporting. The project encompasses software as a service (SaaS) deployment, ensuring HIPAA compliance and offering extensive training for clinical staff. The anticipated project timeline includes a 12-month base period with optional extensions and deliverables such as comprehensive training sessions and monthly usage reports. Critical technical support will be available 24/7, with oversight from a team of subject matter experts in pharmacokinetics. This innovative approach aims to optimize vancomycin dosing, enhance antimicrobial stewardship, and reduce clinical workload, ultimately improving patient outcomes and healthcare costs at WRNMMC.
    55- Synopsis-Soliciation Combo (PR 12258238).docx
    The Defense Health Agency is soliciting proposals for a Bayesian precision dosing software system aimed at predicting future AUC or serum levels and toxicity probabilities for use in the Department of Pharmacy at Walter Reed National Military Medical Center. The request, identified by Solicitation ID 12258238, is designated as a small business set-aside and is structured as a Request for Quotes (RFQ). The software services required will span multiple years from June 2025 to May 2030. Interested vendors must submit offers by May 23, 2025. Evaluation criteria include price, technical acceptability, and adherence to solicitation requirements, which include compliance with federal acquisition regulations. The document incorporates mandatory clauses from the Federal Acquisition Regulation (FAR) and Defense Federal Acquisition Regulation Supplement (DFARS), emphasizing adherence to relevant laws and standards. The primary point of contact for this requirement is Contract Specialist Cinthia Funes, whose contact details are provided. This solicitation highlights the Department's commitment to advancing healthcare technology while ensuring compliance with procurement standards.
    Lifecycle
    Title
    Type
    12258238 -Synopsis/Solicitation for Bayesian precision dosing software system
    Currently viewing
    Solicitation
    Similar Opportunities
    Defense Health Agency Data Governance Transforming the Data Landscape: A Strategic Imperative for Modern Healthcare in Support of Military Readiness
    Dept Of Defense
    The Defense Health Agency (DHA) is seeking proposals from qualified small businesses to provide contractor support for advancing enterprise data readiness and governance within the Military Health System. The primary objectives include developing a comprehensive baseline data inventory, establishing a centralized metadata repository, conducting an Analysis of Alternatives for an enterprise data catalog, and implementing automated metadata harvesting tools to enhance data accessibility and usability. This initiative is crucial for improving decision-making and operational efficiency in military healthcare, with a total contract value of $34 million and a performance period from January 30, 2026, to January 29, 2027, with options for additional 12-month periods. Interested parties should direct inquiries to Linda M. Walker or Andrea V. Rivas via email, and proposals must be submitted electronically by January 9, 2026.
    Customer Care Prototyping - Commercial Solution Opening (Notice of Availability)
    Dept Of Defense
    The Defense Health Agency (DHA) is seeking innovative solutions through its "Customer Care Prototyping 2025-2026" initiative, aimed at enhancing customer care within the Military Health System (MHS). This opportunity invites prototype projects under the authority of 10 U.S.C. § 4022, focusing on developing a foundational platform that prioritizes agile development, self-service support, and data-driven insights to improve mission effectiveness and customer sentiment while reducing costs. Interested vendors should monitor SAM for updates regarding submission instructions and evaluation criteria, with the first "Season Notice" expected in Q1 FY26. For inquiries, contact Gabriela Hurte at gabriela.y.hurte.civ@health.mil or Sonya Edom at sonya.m.edom.civ@health.mil.
    Department of Defense Pharmacy Uniform Formulary Blanket Purchase Agreement/ Uniform Formulary Additional Discount Program
    Dept Of Defense
    The Department of Defense, through the Defense Health Agency (DHA), is soliciting quotes for a Blanket Purchase Agreement (BPA) and an Additional Discount Program (ADP) for pharmaceutical agents to be included in the DoD Uniform Formulary (UF). This procurement aims to establish an effective pharmacy benefits program for the Military Health System (MHS), focusing on oncological agents for myelofibrosis and antihemophilic agents, with evaluations based on clinical and cost-effectiveness. Interested vendors must submit their quotes by January 16, 2026, with a pre-quotation teleconference scheduled for November 20, 2025. For further inquiries, contact Tracy Banks at tracy.e.banks2.civ@health.mil or Stephanie Erpelding at stephanie.j.erpelding.civ@health.mil.
    Residency Management Suite Software and Maintenance
    Dept Of Defense
    The Department of Defense, through the Defense Health Agency (DHA), intends to sole source the procurement of the Residency Management Suite Software and its maintenance from Qgenda, LLC. This proprietary software is essential for unifying program and resident information into a centralized data warehouse, facilitating compliance with Accreditation Council Graduate Medical Education (ACGME) requirements for 36 Graduate Medical Education (GME) and 22 Graduate Allied Health programs, which collectively support over 700 residents and fellows annually. The software's capabilities are critical for accreditation tracking and management of GME work hours, ensuring the continuity of training for military medical professionals. The estimated value of this contract is $97,000, with an anticipated award date of December 31, 2025. Interested parties may submit capability statements to the primary contact, Rebecca Quint, at rebecca.d.quint.civ@health.mil, by 4:00 PM CT on December 19, 2025.
    Department of Defense Pharmacy Uniform Formulary Blanket Purchase Agreement/Uniform Formulary Additional Discount Program
    Dept Of Defense
    The Department of Defense (DoD) is issuing a Request for Quotation (RFQ) for pharmaceutical agents to be included in the Uniform Formulary (UF) as part of a Blanket Purchase Agreement (BPA) and Additional Discount Program (ADP) for Military Treatment Facilities (MTFs) and TRICARE pharmacies. This procurement aims to establish an effective pharmacy benefits program for the Military Health System (MHS), focusing on the clinical and cost-effectiveness of drugs, which will be evaluated by the Pharmacy and Therapeutics (P&T) Committee. Key drugs under consideration include newly approved agents for lung cancer, antihypertensive agents, oncological agents, diuretics, antilipidemics, and targeted immunomodulatory biologics, with quotes due by January 5, 2026, for a committee meeting scheduled for February 4-5, 2026. Interested manufacturers should contact Tracy Banks or Julia Trang via email for further details and ensure compliance with submission requirements outlined in the RFQ document HT9402-26-Q-9103.
    Health Care Delivery Solutions (HCDS) Electronic Health Record Follow-on (MHS GENESIS)
    Dept Of Defense
    The Department of Defense, through the Defense Health Agency (DHA), is seeking industry input for the Health Care Delivery Solutions (HCDS) Electronic Health Record (EHR) Follow-on (MHS GENESIS) procurement. This initiative aims to modernize the DoD's healthcare management system by enhancing interoperability, optimizing patient care, and leveraging commercial technology advancements while ensuring efficient integration with the Department of Veterans Affairs (VA). The procurement process is critical for maintaining a robust electronic health record system that serves approximately 9.6 million beneficiaries and 194,000 users. Interested parties are encouraged to submit their responses to the Request for Information (RFI) by November 17, 2025, and can direct inquiries to Sonya Edom at sonya.m.edom.civ@health.mil or Gabriela Hurte at gabriela.y.hurte.civ@health.mil. The anticipated timeline includes a draft RFP in Q1 FY26 and contract awards by Q4 FY26.
    TRICARE Pharmacy Program RFI
    Dept Of Defense
    The Defense Health Agency (DHA) is conducting a Request For Information (RFI) for its next-generation TRICARE Pharmacy Program (TPharm) contract, aimed at gathering industry feedback to inform the program's requirements and design. The RFI focuses on key areas such as pharmacy benefit administration, mail order pharmacy fulfillment, enhanced care programs, and operational barriers affecting vendor participation in federal pharmacy contracts. This program is crucial as it serves over 9.6 million beneficiaries and integrates various pharmacy services, including retail and mail order options. Interested parties are encouraged to submit their responses via email to dha.buckley.ad-spt-cae.mbx.tpharm6@health.mil by January 30, 2026, at 12:00 pm MST, as the DHA seeks to utilize this information for market research purposes.
    Commvault Software
    Dept Of Defense
    The Defense Health Agency (DHA) has awarded a contract for Commvault Software to V3Gate LLC, as part of a NASA SEWP Fixed Price Requirement. This software serves as an enterprise-level data management platform, providing essential capabilities for data backup, recovery, archiving, and disaster recovery across both on-premises and cloud infrastructures. The awarded contract, which was granted on September 24, 2025, is structured with a base year and no option periods, ensuring that the DHA's readiness requirements are met. For further inquiries, interested parties can contact Melissa Hearst at melissa.l.hearst.ctr@health.mil or by phone at 210-221-6237.
    Program Executive Office, Defense Healthcare Management Systems (PEO DHMS), Commercial Solutions Opening (CSO)
    Dept Of Defense
    The Department of Defense, through the Defense Health Agency (DHA), is issuing a Commercial Solutions Opening (CSO) to solicit proposals for prototype projects aimed at enhancing the effectiveness of healthcare delivery for military personnel. This initiative seeks innovative solutions that improve platforms, systems, components, or materials utilized by the Department of Defense, particularly in the realm of electronic health records and data management. The CSO will remain open until July 1, 2026, and interested parties are encouraged to submit their proposals, ensuring they adhere to the guidelines outlined in the associated documents. For inquiries, potential respondents can contact Lacey Lockard at lacey.n.lockard.civ@health.mil or Elizabeth Holten at elizabeth.l.holten.civ@health.mil.
    Physician Scheduling Software
    Veterans Affairs, Department Of
    The Department of Veterans Affairs is seeking proposals for a web-based Physician Scheduling Software for the Puget Sound VA Health Care System. The software must support 45 annual licenses and provide training and 24/7 support for managing various medical providers' on-call, clinic, rotation, and shift schedules, with the current system, Amion for Enterprises+, serving as a benchmark for evaluation. This procurement is critical for enhancing scheduling efficiency within the healthcare system, and the contract will span a base year from January 1, 2026, to December 31, 2026, with two optional years following. Interested vendors must submit their quotes via email to Amy Kuczajda at Amy.Kuczajda@va.gov by 3 PM MST on December 23, 2025, adhering to the specified FAR and VAAR clauses regarding compliance and electronic payment.