The National Institutes of Health (NIH) is offering a funding opportunity titled "In Vivo Non-Invasive Optical Imaging Approaches for Biological Systems" under the cooperative agreement mechanism (UG3/UH3), aimed at advancing optical imaging technologies to address the challenges of light scattering in biological tissues. This initiative seeks to develop next-generation non-invasive or minimally-invasive optical imaging techniques that enhance penetration depth and resolution, thereby improving diagnostic and research capabilities in biomedical fields. With a total funding commitment of approximately $4.9 million available over a maximum project period of three years, eligible applicants include higher education institutions, non-profits, and small businesses, all of which must submit their proposals electronically through Grants.gov by February 7, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.