Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)
ID: 350947Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $500K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/350947

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DC-24-005.html
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for a cooperative agreement aimed at developing in vivo high-resolution imaging technologies for the human inner ear, under the funding opportunity titled "Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)." This initiative seeks to support high-risk clinical trials that enhance imaging techniques to visualize inner ear structures with greater detail and accuracy, focusing on improving existing modalities or developing new imaging probes and contrast agents for non-invasive applications. The funding opportunity, which anticipates approximately $2 million to support 2-4 projects annually over five years, is open to a wide range of eligible applicants, including universities, nonprofits, and federal entities. Interested parties should note that applications are due by June 3, 2025, and can find further details at the NIH Grants Information website or by contacting grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DC-24-005-Full-Announcement.html
    RFA-DC-24-005.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), invites applications for cooperative agreements focused on developing in vivo high-resolution imaging technologies for the human inner ear, under the funding opportunity title RFA-DC-24-005. This funding aims to support clinical trials that provide significant advancements in imaging techniques to visualize inner ear structures more effectively, with a particular emphasis on addressing high-risk clinical trials requiring FDA oversight. Proposals may revolve around improving existing imaging modalities, developing new imaging probes, or enabling non-invasive imaging for advanced diagnosis and treatment of auditory and vestibular disorders. Eligibility spans a wide range of organizations, including universities, nonprofits, and federal entities, with a total anticipated funding of approximately $2 million to support 2-4 projects annually over five years. Applications must include a comprehensive research strategy, demonstrate a significant increase in imaging resolution, and articulate potential clinical applications. Key dates for submission begin on January 1, 2024, with multiple deadlines throughout 2025. This initiative aligns with NIH's mission to advance research that enhances human health by overcoming current technological limitations in inner ear imaging.
    Similar Opportunities
    In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "In Vivo High-Resolution Imaging for Inner Ear Visualization," aimed at advancing imaging technologies for the non-invasive visualization of the inner ear in living patients. This initiative seeks to support the development of both new and improved imaging techniques that can provide detailed insights into inner ear structures, such as hair cells and membranes, with a focus on applications that can be utilized in awake patients. The program is particularly significant for enhancing the diagnosis and treatment of inner ear disorders, reflecting NIH's commitment to innovative health research. A total of $2 million is allocated for 2-4 awards in fiscal year 2024, with applications opening on January 1, 2024, and a closing date for submissions set for June 3, 2025. Interested applicants can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    In Vivo Non-Invasive Optical Imaging Approaches for Biological Systems (UG3/UH3 Clinical Trials Not Allowed
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "In Vivo Non-Invasive Optical Imaging Approaches for Biological Systems" under the cooperative agreement mechanism (UG3/UH3), aimed at advancing optical imaging technologies to address the challenges of light scattering in biological tissues. This initiative seeks to develop next-generation non-invasive or minimally-invasive optical imaging techniques that enhance penetration depth and resolution, thereby improving diagnostic and research capabilities in biomedical fields. With a total funding commitment of approximately $4.9 million available over a maximum project period of three years, eligible applicants include higher education institutions, non-profits, and small businesses, all of which must submit their proposals electronically through Grants.gov by February 7, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute on Deafness and Other Communication Disorders (NIDCD), is offering a funding opportunity titled "NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)." This initiative aims to support cooperative agreements for clinical trials that require FDA oversight, are intended to establish efficacy, or present higher risks to participants, with a budget exceeding $700,000. The funding is crucial for advancing clinical practices in treating communication disorders, emphasizing the inclusion of diverse populations in recruitment and retention strategies. Interested applicants, including various educational and nonprofit organizations, must submit their applications by January 27, 2024, and can find more information at NIH Grants.
    BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for clinical studies aimed at advancing next-generation devices for recording and modulation in the human central nervous system, under the BRAIN Initiative. This initiative seeks to support small clinical trials that provide critical data necessary for the development of devices intended to treat central nervous system disorders, particularly those requiring an Investigational Device Exemption (IDE) from the FDA. The funding is crucial for enhancing neurotechnology and improving treatment outcomes, with NIH planning to allocate approximately $10 million annually for 5 to 7 awards, each with a maximum budget of $1.5 million per year for up to five years. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with applications due by September 28, 2026.
    NEI Cooperative Agreement for Early-Stage Clinical Trials with Greater than Minimal Risk (U01 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity through the National Eye Institute (NEI) for cooperative agreements (U01) aimed at supporting early-stage clinical trials that involve greater than minimal risk, specifically targeting interventions for vision disorders. This initiative encourages applications for Phase I or II trials that are backed by strong preliminary data and require compliance with NIH guidelines, including the establishment of a Data Monitoring and Safety Committee (DSMC) for safety oversight. The funding is crucial for advancing research in the screening, diagnosis, prevention, and treatment of vision disorders, with project budgets reflecting actual needs and a maximum project period of five years. Interested applicants can find more information and contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov, with the application deadline set for May 7, 2025.
    NIDCD's Mentored Research Education Pathway for Otolaryngology Residents and Medical Students (R25 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced the NIDCD's Mentored Research Education Pathway for Otolaryngology Residents and Medical Students (R25), aimed at enhancing recruitment into research careers within the biomedical field. This program supports educational activities that provide mentorship and research opportunities for medical students and resident-investigators, addressing the shortage of clinician-investigators in otolaryngology. Eligible applicants include higher education institutions and nonprofits, with a focus on fostering diversity among participants, and funding is capped at $499,999 in direct costs per year for a duration of 12 to 24 months. Interested parties can find more information and apply by contacting NIH Grants Information at grantsinfo@nih.gov, with applications due by September 29, 2026.
    Notice of Intent to Publish a Funding Opportunity Announcement for In Vivo Non-Invasive Optical Approaches for Biological systems (UG3/HU3 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is planning to publish a Notice of Funding Opportunity (NOFO) for the "Advancing Non-Invasive Optical Approaches for Biological Systems" initiative, aimed at developing next-generation optical imaging techniques. This initiative seeks to address the challenges of light scattering in biological systems, enabling high-resolution imaging at greater depths within tissues, and will support three-year bi-phasic research projects through UG3/UH3 Cooperative Agreements. With an estimated total program funding of $4.9 million and an award ceiling of $1.6 million, the NIH anticipates issuing the NOFO in December 2024, with applications due by March 2025 and awards expected to be made by December 2025. Interested applicants are encouraged to prepare collaborative proposals in advance of the official announcement.
    BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System," aimed at enhancing technologies for recording neural activity and addressing significant challenges in neuroscience research. This initiative seeks applications focused on optimizing existing or emerging technologies through iterative testing with end users, with the goal of improving network recording capabilities and developing tools for circuit manipulation that can be validated in vivo. The funding, anticipated at $10 million per year for 15-20 awards, requires applicants to include a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research, with submissions due by January 20, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute on Deafness and Other Communication Disorders (NIDCD), is offering research grants aimed at translating basic research findings into clinical practice, specifically for communication disorders. This funding opportunity encourages collaborations between basic scientists and clinicians to develop practical applications that address hearing, balance, smell, taste, voice, and language disorders, with a focus on milestone-driven proposals that demonstrate a clear connection to clinical conditions and impactful outcomes. The grants, limited to a maximum of $500,000 in direct costs annually, are expected to support 2-3 awards in FY25, with applications due by October 12, 2027. Interested applicants can find more information and submit their proposals through Grants.gov, and may contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the BRAIN Initiative, specifically targeting the optimization of instrumentation and device technologies for recording and modulation in the nervous system. This funding opportunity aims to enhance the understanding of neural circuits by supporting projects that utilize innovative technologies, such as optical, electrical, magnetic, or acoustic methodologies, to address significant challenges in neuroscience research. Successful proposals should demonstrate a commitment to interdisciplinary collaboration and include a Plan for Enhancing Diverse Perspectives (PEDP) to foster inclusivity among diverse teams and institutions. The initiative anticipates awarding approximately $10 million across 15-20 projects, with applications due by January 20, 2026. For further details, interested applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-017.html.