Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)
ID: 350947Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $500K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/350947

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DC-24-005.html
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for a cooperative agreement aimed at developing in vivo high-resolution imaging technologies for the human inner ear, under the funding opportunity titled "Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)." This initiative seeks to support high-risk clinical trials that enhance imaging techniques to visualize inner ear structures with greater detail and accuracy, focusing on improving existing modalities or developing new imaging probes and contrast agents for non-invasive applications. The funding opportunity, which anticipates approximately $2 million to support 2-4 projects annually over five years, is open to a wide range of eligible applicants, including universities, nonprofits, and federal entities. Interested parties should note that applications are due by June 3, 2025, and can find further details at the NIH Grants Information website or by contacting grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DC-24-005-Full-Announcement.html
    RFA-DC-24-005.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), invites applications for cooperative agreements focused on developing in vivo high-resolution imaging technologies for the human inner ear, under the funding opportunity title RFA-DC-24-005. This funding aims to support clinical trials that provide significant advancements in imaging techniques to visualize inner ear structures more effectively, with a particular emphasis on addressing high-risk clinical trials requiring FDA oversight. Proposals may revolve around improving existing imaging modalities, developing new imaging probes, or enabling non-invasive imaging for advanced diagnosis and treatment of auditory and vestibular disorders. Eligibility spans a wide range of organizations, including universities, nonprofits, and federal entities, with a total anticipated funding of approximately $2 million to support 2-4 projects annually over five years. Applications must include a comprehensive research strategy, demonstrate a significant increase in imaging resolution, and articulate potential clinical applications. Key dates for submission begin on January 1, 2024, with multiple deadlines throughout 2025. This initiative aligns with NIH's mission to advance research that enhances human health by overcoming current technological limitations in inner ear imaging.
    Similar Opportunities
    In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)" aimed at advancing imaging technologies for the inner ear. This initiative seeks to support the development of innovative in vivo imaging techniques that can visualize the inner ear's structures with enhanced detail and accuracy, thereby improving the diagnosis and treatment of auditory and vestibular disorders. The program encourages a multidisciplinary approach and supports low-risk clinical trials, with an estimated total funding of $500,000 available for 4-6 awards in FY 2025. Applications are due by May 3, 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is announcing a funding opportunity titled "Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 Clinical Trial Optional)." This initiative aims to solicit research applications focused on developing advanced non-invasive and minimally invasive imaging technologies to visualize the human olfactory system, addressing the current limitations in imaging techniques that hinder understanding of olfactory disorders. The opportunity emphasizes the need for multimodal approaches and encourages collaborations among experts in various fields such as olfaction, biomedical imaging, and bioengineering. Interested applicants should note that applications are not currently being solicited, but they can prepare for submission as the estimated synopsis post date is October 27, 2025, with a closing date of November 27, 2025. For further inquiries, potential applicants can contact Dr. Merav Sabri at merav.sabri@nih.gov or by phone at 301-827-5992.
    NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity through the National Institute on Deafness and Other Communication Disorders (NIDCD) for cooperative agreements aimed at supporting clinical trials in communication disorders. Applicants are required to propose a single clinical trial that may necessitate FDA oversight, demonstrate efficacy, or involve higher risks, with an emphasis on substantial interaction with NIDCD staff and comprehensive protections for human subjects. This initiative is crucial for advancing research and establishing effective treatments for conditions related to hearing, balance, taste, smell, voice, speech, and language. Interested applicants can access further details and guidelines through the announcement available at NIH Grants, with a budget that may exceed $700,000 in specific circumstances and a closing date for applications set for October 18, 2027.
    NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional) aimed at advancing the diagnosis, prevention, treatment, and amelioration of human sensory and communication disorders. This funding opportunity supports integrated, multidisciplinary research programs that include 3-4 synergistic research projects and an administrative core, with the possibility of 1-2 optional scientific cores, all centered around a unifying clinical theme. The maximum project period is five years, with budgets capped at $1,500,000 in direct costs per year for new applications. Eligible applicants include various organizations, excluding foreign entities, and are encouraged to consult with NIDCD staff prior to submission to ensure responsiveness. The application deadline is June 2, 2028, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute on Deafness and Other Communication Disorders (NIDCD), is offering a funding opportunity titled "NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)." This initiative aims to support cooperative agreements for clinical trials that require FDA oversight, are intended to establish efficacy, or present higher risks to participants, with a budget exceeding $700,000. The funding is crucial for advancing clinical practices in treating communication disorders, emphasizing the inclusion of diverse populations in recruitment and retention strategies. Interested applicants, including various educational and nonprofit organizations, must submit their applications by January 27, 2024, and can find more information at NIH Grants.
    BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for clinical studies aimed at advancing next-generation devices for recording and modulation in the human central nervous system, under the BRAIN Initiative. This initiative seeks to support small clinical trials that provide critical data necessary for the development of devices intended to treat central nervous system disorders, particularly those requiring an Investigational Device Exemption (IDE) from the FDA. The funding is crucial for enhancing neurotechnology and improving treatment outcomes, with NIH planning to allocate approximately $10 million annually for 5 to 7 awards, each with a maximum budget of $1.5 million per year for up to five years. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with applications due by September 28, 2026.
    NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a Clinical Research Center Grant (P50 Clinical Trial Optional) aimed at advancing research in the areas of hearing, balance, smell, taste, voice, speech, or language. This grant encourages small businesses to form multidisciplinary teams that will collaborate on a synergistic set of 3-4 research projects addressing a unifying theme related to sensory and communication disorders. The initiative is designed to foster innovative solutions to complex clinical problems through integrated research efforts, supported by an administrative core and optional scientific cores. Interested applicants should note that while applications are not currently being solicited, they are encouraged to prepare for the upcoming Notice of Funding Opportunity (NOFO), with an estimated synopsis posting date of August 6, 2025, and a close date of October 7, 2025. For further inquiries, potential applicants can contact Holly Storkel, Ph.D., at holly.storkel@nih.gov or by phone at 301-496-5061.
    NIDCD's Mentored Research Education Pathway for Otolaryngology Residents and Medical Students (R25 - Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced the NIDCD's Mentored Research Education Pathway for Otolaryngology Residents and Medical Students (R25), aimed at enhancing recruitment into research careers within the biomedical field. This program supports educational activities that provide mentorship and research opportunities for medical students and resident-investigators, addressing the shortage of clinician-investigators in otolaryngology. Eligible applicants include higher education institutions and nonprofits, with a focus on fostering diversity among participants, and funding is capped at $499,999 in direct costs per year for a duration of 12 to 24 months. Interested parties can find more information and apply by contacting NIH Grants Information at grantsinfo@nih.gov, with applications due by September 29, 2026.
    Notice of Intent to Publish a Funding Opportunity Announcement for In Vivo Non-Invasive Optical Approaches for Biological systems (UG3/HU3 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is planning to publish a Notice of Funding Opportunity (NOFO) for the "Advancing Non-Invasive Optical Approaches for Biological Systems" initiative, aimed at developing next-generation optical imaging techniques. This initiative seeks to address the challenges of light scattering in biological systems, enabling high-resolution imaging at greater depths within tissues, and will support three-year bi-phasic research projects through UG3/UH3 Cooperative Agreements. With an estimated total program funding of $4.9 million and an award ceiling of $1.6 million, the NIH anticipates issuing the NOFO in December 2024, with applications due by March 2025 and awards expected to be made by December 2025. Interested applicants are encouraged to prepare collaborative proposals in advance of the official announcement.
    BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System," aimed at enhancing technologies for recording neural activity and addressing significant challenges in neuroscience research. This initiative seeks applications focused on optimizing existing or emerging technologies through iterative testing with end users, with the goal of improving network recording capabilities and developing tools for circuit manipulation that can be validated in vivo. The funding, anticipated at $10 million per year for 15-20 awards, requires applicants to include a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research, with submissions due by January 20, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.