The National Institutes of Health (NIH) has announced a funding opportunity titled "Mechanistic Investigations into ADRD Associated Protein Structures in Biological Settings" (Funding Opportunity Number PAR-24-234) aimed at advancing research on Alzheimer’s disease-related dementias (ADRD). This initiative encourages researchers to utilize in-cell structural biology methodologies to investigate the molecular and cellular mechanisms of ADRD, focusing on high-resolution characterization of protein structures in their native environments. The program offers up to $3 million annually for five years, with a maximum of $500,000 in direct costs per project per year. Applications must be submitted electronically through Grants.gov by October 4, 2024, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.