Mechanistic Investigations into ADRD Associated Protein Structures in Biological Settings (R01 - Clinical Trial Not Allowed)
ID: 354716Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $500K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/354716

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-234.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Mechanistic Investigations into ADRD Associated Protein Structures in Biological Settings" (Funding Opportunity Number PAR-24-234) aimed at advancing research on Alzheimer’s disease-related dementias (ADRD). This initiative encourages researchers to utilize in-cell structural biology methodologies to investigate the molecular and cellular mechanisms of ADRD, focusing on high-resolution characterization of protein structures in their native environments. The program offers up to $3 million annually for five years, with a maximum of $500,000 in direct costs per project per year. Applications must be submitted electronically through Grants.gov by October 4, 2024, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-234-Full-Announcement.html
    PAR-24-234.html
    The Department of Health and Human Services (HHS), specifically the National Institutes of Health (NIH), has announced a new funding opportunity titled "Mechanistic Investigations into ADRD Associated Protein Structures in Biological Settings" (Funding Opportunity Number PAR-24-234). This initiative aims to support research leveraging in-cell structural biology methodologies to explore the molecular and cellular mechanisms underlying Alzheimer’s disease-related dementias (ADRD). Researchers are encouraged to focus on high-resolution determination of ADRD-linked protein structures in native settings and further develop research tools to characterize structural findings. The program will provide up to $3 million annually for five years, with a cap of $500,000 direct costs per project per year. Eligible applicants include various educational institutions, nonprofits, and governmental organizations, while applications must be submitted electronically through Grants.gov by the specified deadlines. This funding aligns with the NIH's overarching goals to improve understanding of ADRD and enhance diagnostic tools and treatment strategies. Compliance with application guidelines and early submissions are emphasized to account for potential errors. Overall, this funding opportunity aims to significantly advance mechanistic understandings of ADRD through innovative structural studies.
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