The National Institutes of Health (NIH), in collaboration with the Global Alliance for Chronic Diseases (GACD), is inviting applications for a grant focused on implementation research aimed at managing non-communicable diseases (NCDs) among individuals with multiple chronic conditions in low- and middle-income countries (LMICs) and U.S. Tribal populations. The objective is to develop effective, equitable, and integrated patient-centered care approaches that prioritize the unique social and cultural contexts of the targeted populations, with an emphasis on health equity and stakeholder engagement. This initiative is crucial for enhancing global health outcomes related to NCD multimorbidity and aims to build research capacity and sustainability beyond the initial funding period. The estimated total program funding is $500,000, with applications due by January 7, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-25-213.html.