Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (U43/U44 Clinical Trials Not Allowed)
ID: 347582Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $296K

Eligible Applicants

Small Businesses

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/347582

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-23-267.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine" (PAR-23-267) aimed at supporting the development of novel extracellular vesicle (EV)-based therapeutic platforms. This initiative specifically invites U.S. small businesses to apply for Small Business Innovation Research (SBIR) grants, focusing on overcoming challenges in the production and manufacturing of EVs for tissue and organ repair, with an emphasis on demonstrating GMP-grade production and facilitating regulatory approval. The funding mechanism includes cooperative agreements (U43/U44), with a budget cap of $295,924 for Phase I and $1,972,828 for Phase II awards, and applications must adhere to stringent guidelines and undergo peer review. Interested applicants can find more information and submit inquiries via the NIH Grants Information email at grantsinfo@nih.gov, with the application deadline set for June 6, 2025.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-23-267-Full-Announcement.html
    PAR-23-267.html
    The Department of Health and Human Services, through the NIH, has launched a funding opportunity (PAR-23-267) to support the development of novel extracellular vesicle (EV)-based therapeutic platforms for regenerative medicine. This initiative invites U.S. small business concerns to apply for Small Business Innovation Research (SBIR) grants aimed at addressing challenges in the production and manufacturing of EVs for tissue and organ repair. Key objectives include demonstrating GMP-grade production, assessing therapeutic benefits, and facilitating regulatory approval. The funding mechanism, specifically U43 and U44 cooperative agreements, highlights an interest in innovative approaches to harness EVs for therapeutic applications. Grant applications must demonstrate a viable commercialization plan and address the expected commercial impact. Eligible applicants must be U.S.-based and meet specific ownership and size criteria, with a total budget cap of $295,924 for Phase I and $1,972,828 for Phase II awards. The application process requires compliance with stringent guidelines and is subject to peer review focusing on feasibility, significance, and innovation. This effort reflects the NIH's commitment to advancing regenerative medicine through partnerships with small businesses, facilitating innovations aimed at improving therapeutic outcomes for various diseases.
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