Cooperative AgreementPostedDiscretionary

Miniaturization and Automation of Tissue Chip Systems (MATChS) (UT1/UT2 - Clinical Trial Not Allowed)

National Institutes of Health
RFA-TR-23-018
Application Deadline
Feb 23, 2026
Closed
Days Remaining
0
Deadline passed
Award Ceiling
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH) is offering a funding opportunity titled "Miniaturization and Automation of Tissue Chip Systems (MATChS)" aimed at U.S. small business concerns through STTR Phase I and II cooperative agreements. The initiative seeks to develop innovative microphysiological systems (MPS) that replicate human organ functions for drug discovery and biomedical research, addressing the limitations of traditional methods that are often costly and time-consuming. This funding opportunity is crucial for advancing tissue chip technology, enhancing the accessibility and usability of these systems in research, and supporting safe therapeutic assessments. Interested applicants can apply for a total funding commitment of up to $2.15 million, with key submission dates including an open date for applications on January 22, 2024, and a closing date of February 23, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-TR-23-018.html.

Eligible Applicants

Small Businesses
Additional Eligibility Information

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Grant Documents

2 Files
RFA-TR-23-018-Full-Announcement.html
HTML0 KBAug 24, 2024
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RFA-TR-23-018.html
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AI Summary
The Department of Health and Human Services, through the National Institutes of Health (NIH), announces the Miniaturization and Automation of Tissue Chip Systems (MATChS) funding opportunity. This initiative invites U.S. small business concerns to submit applications for STTR Phase I and II cooperative agreements. The MATChS aims to develop innovative microphysiological systems (MPS) that mimic human organ functions for drug discovery and biomedical research, addressing challenges in traditional methods that are costly and time-consuming. Objectives include creating portable and automated MPS platforms with integrated sensors for high-throughput data analysis. The initiative builds upon previous collaborations between NIH, NCATS, and NASA, enhancing accessibility and usability of tissue chips in research. Key dates include an open date for submissions on January 22, 2024, and a funding commitment of up to $2.15 million for two Phase I awards and one Phase II award in FY 2024. The announcement emphasizes the need for milestone-driven projects with active NIH involvement in their development. Eligible applicants must be organized for profit, have a significant U.S. presence, and meet specific ownership and employee criteria. The MATChS serves to further the field of tissue chip technology, supporting safe and efficient therapeutic assessments while driving towards commercialization and practical application in clinical settings.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedNov 21, 2023
deadlineApplication DeadlineFeb 23, 2026
expiryArchive DateMar 31, 2026

Funding Details

No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Cooperative Agreement

Grantor Contact

CFDA Numbers

93.350

Official Sources