Miniaturization and Automation of Tissue Chip Systems (MATChS) (U43/U44 Clinical Trial Not Allowed)

Active
Yes
Status
Posted
Published Date
November 21st, 2023
Close Date
February 23rd, 2026
Opportunity No.
RFA-TR-23-017

Agency

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Small Businesses

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Summary

The National Institutes of Health (NIH) has posted a grant opportunity titled "Miniaturization and Automation of Tissue Chip Systems (MATChS)" under the category of Health. This opportunity is a Cooperative Agreement and does not require cost sharing or matching. The grant is open to Small Businesses. The purpose of this grant is to support the development of MATChS through the SBIR cooperative agreement mechanisms. The goal is to fund research and development projects that focus on creating tools and turnkey technologies for higher throughput automated measures with on-line sensing. The aim is to reduce manual handling and enable rapid acquisition and analysis of data. The ultimate outcome of the funded projects will be the availability of miniaturized automated tissue chip platforms. These platforms will be used in drug development and various biomedical research laboratories. As a cooperative agreement, small business concerns (SBCs) are expected to develop milestones and benchmarks. They will work closely with NIH staff to ensure progress in the project's aims, which include the development of an automated system and demonstrable pathways to commercialization. The closing date for this grant opportunity is February 23, 2026. For more information and to apply, please visit the following link: Miniaturization and Automation of Tissue Chip Systems (MATChS) Grant Opportunity. If you have any inquiries, please contact NIH Grants Information at grantsinfo@nih.gov.

Description

This NOFO provides support using the SBIR cooperative agreement mechanisms for the development of MATChS. Applications considered responsive to this would include those proposing research and development of tools and turnkey technologies for higher throughput automated measures with on-line sensing, rapid acquisition and analysis of data to reduce manual handling. Funded projects will result in an increased availability of miniaturized automated tissue chip platforms for use in drug development and across multiple applications as a major research tool in biomedical research laboratories. As a cooperative agreement, small business concerns (SBCs) will be expected to develop milestones and benchmarks, and work with NIH staff towards progress in the aims of the project to develop an automated system and demonstrable pathways to commercialization.

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The National Institutes of Health (NIH) has posted a grant opportunity titled "Miniaturization and Automation of Tissue Chip Systems (MATChS) (UT1/UT2 - Clinical Trial Not Allowed)". This opportunity falls under the category of Health and is a Cooperative Agreement funding instrument type. Small businesses are eligible to apply for this grant. The purpose of this grant is to support the development of MATChS using the Small Business Technology Transfer (STTR) cooperative agreement mechanisms. The goal is to fund research and development projects that focus on the creation of tools and turnkey technologies for higher throughput automated measures with on-line sensing. The aim is to reduce manual handling and enable rapid acquisition and analysis of data. The ultimate outcome of the funded projects will be the availability of miniaturized automated tissue chip platforms. These platforms will be used in drug development and various biomedical research laboratories. As a cooperative agreement, small business concerns (SBCs) are expected to develop milestones and benchmarks. They will work closely with NIH staff to make progress in the project's aims, which include the development of an automated system and demonstrable pathways to commercialization. The grant opportunity does not require cost sharing or matching. The deadline for applications is February 23, 2026, and the archive date is March 31, 2026. For more information and to apply, interested parties can visit the following website: [http://grants.nih.gov/grants/guide/rfa-files/RFA-TR-23-018.html](http://grants.nih.gov/grants/guide/rfa-files/RFA-TR-23-018.html). Any inquiries can be directed to NIH Grants Information at grantsinfo@nih.gov.
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