BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)
ID: 354583Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity under the BRAIN Initiative, titled "Brain-Behavior Quantification and Synchronization: Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)." This initiative seeks applications that propose innovative research to develop and validate advanced tools for the high-resolution measurement of behavior in non-human animal models, while integrating behavioral, neural, and environmental data to understand behavior as a complex dynamic system. The funding, estimated at $8 million, supports projects with a maximum duration of five years and requires a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research. Interested applicants should refer to the full announcement for detailed instructions and submit their proposals by October 9, 2026, to the NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    Files
    Title
    Posted
    The National Institutes of Health's (NIH) Department of Health and Human Services has announced a funding opportunity focused on the BRAIN Initiative: Brain-Behavior Quantification and Synchronization (BBQS). This initiative aims to support research that uses non-human animal models to develop, validate, and apply innovative methods for the multidimensional measurement of behavior and neural activity. The goal is to enhance understanding of behavior as a complex dynamic system by integrating behavioral, neural, and environmental data. Key objectives include forming interdisciplinary teams, creating advanced sensing technologies, and producing computational models that capture behavior-environment relationships. Proposals must incorporate a Plan for Enhancing Diverse Perspectives (PEDP) to foster inclusivity in research. With an estimated funding of $8 million, NIH invites applications with a maximum project duration of five years, with an emphasis on novel methodologies that push the boundaries of traditional research paradigms. The application process involves comprehensive instructions, including adherence to NIH Grants Policy, and requires significant support from participating NIH institutes. This funding opportunity reflects NIH's commitment to advancing behavioral science and improving public health through innovative interdisciplinary research.
    Similar Opportunities
    BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative and Integrative Models of Behavior at the Organismal Level," aimed at advancing behavioral science through innovative research. This initiative seeks applications that focus on developing and validating tools for minimally invasive, high-resolution measurement of behavior, integrating multidimensional behavioral, neural, and environmental data, and creating new theoretical models to understand behavior as a complex dynamic system. With an anticipated funding commitment of approximately $8 million, the program emphasizes interdisciplinary collaboration and requires a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity. Interested applicants should submit their proposals by October 9, 2026, and can direct inquiries to grantsinfo@nih.gov for further information.
    BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative for the development of next-generation sensor technologies and bioelectronic devices, specifically through the Brain Behavior Quantification and Synchronization (BBQS) program. This initiative aims to enhance the measurement of simultaneous behavior and neural activity in various environments, encouraging interdisciplinary collaborations among engineers and behavioral scientists to create compact, reliable sensors that integrate with brain recording data. The NIH plans to allocate approximately $10 million to fund 6-8 awards, with each project lasting up to five years, and requires applicants to submit a Plan for Enhancing Diverse Perspectives to promote inclusivity in research teams. Interested parties can find more information and apply by visiting the official announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-140.html, with applications due by June 15, 2027.
    BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity under the BRAIN Initiative, aimed at developing and validating novel tools to analyze cell-specific and circuit-specific processes in the brain. This initiative seeks proposals that focus on creating innovative technologies to enhance the understanding of complex neural behaviors and interactions, particularly tools that are non-invasive and applicable across various model organisms. The program is critical for advancing research in brain function and disorders, with an estimated funding total of $8 million to support 6-9 awards, and applications are due by May 7, 2024. Interested applicants must submit a Plan for Enhancing Diverse Perspectives (PEDP) and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for clinical studies aimed at advancing next-generation devices for recording and modulation in the human central nervous system, under the BRAIN Initiative. This initiative seeks to support small clinical trials that provide critical data necessary for the development of devices intended to treat central nervous system disorders, particularly those requiring an Investigational Device Exemption (IDE) from the FDA. The funding is crucial for enhancing neurotechnology and improving treatment outcomes, with NIH planning to allocate approximately $10 million annually for 5 to 7 awards, each with a maximum budget of $1.5 million per year for up to five years. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with applications due by September 28, 2026.
    BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System," aimed at enhancing technologies for recording neural activity and addressing significant challenges in neuroscience research. This initiative seeks applications focused on optimizing existing or emerging technologies through iterative testing with end users, with the goal of improving network recording capabilities and developing tools for circuit manipulation that can be validated in vivo. The funding, anticipated at $10 million per year for 15-20 awards, requires applicants to include a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research, with submissions due by January 20, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative, titled "New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)." This initiative aims to support proof-of-concept testing and the development of innovative neurotechnologies that can enhance the understanding of brain circuit dynamics and facilitate transformative neuroscience research. The program encourages high-risk, high-impact projects that integrate diverse scientific domains and require applicants to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposals. The total estimated funding available is $10 million annually, with plans to support 15-20 awards over a maximum project period of three years. Interested applicants must adhere to strict submission guidelines, and the application deadline is January 20, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for the BRAIN Initiative, specifically targeting the development of next-generation sensor technology to enhance the understanding of brain behavior. This initiative aims to solicit applications for research focused on the creation and preclinical testing of innovative sensors and bioelectronics as part of the Brain Behavior Quantification and Synchronization Program. The anticipated NOFO is expected to be published in Fall 2024, with applications due in late Spring 2025, and the estimated award date is set for April 1, 2026. Interested applicants should prepare to collaborate and develop responsive projects, as there are no cost-sharing requirements associated with this cooperative agreement.
    BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System," aimed at advancing neuroscience research through innovative technology development. This initiative seeks applications for the creation of new hardware, software, or molecular constructs that address challenges in recording and modulating neural cells and circuits, with a focus on high-risk projects that could lead to transformative outcomes in understanding dynamic signaling within the central nervous system. The program allocates an estimated $10 million annually for 15-20 awards, emphasizing collaboration across scientific domains and encouraging participation from diverse institutions, particularly those supporting early-career researchers and underserved populations. Interested applicants should note that the application submission deadlines begin on May 2, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative to support clinical studies aimed at advancing next-generation devices for recording and modulation within the human central nervous system (CNS). This initiative encourages proposals for early-stage clinical investigations, including first-in-human studies, that focus on treating CNS disorders and enhancing understanding of brain functions, particularly through Significant Risk studies requiring FDA Investigational Device Exemptions (IDEs) for chronic implants. The NIH plans to allocate approximately $10 million annually to fund 5 to 7 projects, emphasizing the importance of collaborations with device manufacturers through a public-private partnership program, and requires a Plan for Enhancing Diverse Perspectives as part of the application. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with the application deadline set for January 28, 2027.
    BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the BRAIN Initiative, specifically targeting the optimization of instrumentation and device technologies for recording and modulation in the nervous system. This funding opportunity aims to enhance the understanding of neural circuits by supporting projects that utilize innovative technologies, such as optical, electrical, magnetic, or acoustic methodologies, to address significant challenges in neuroscience research. Successful proposals should demonstrate a commitment to interdisciplinary collaboration and include a Plan for Enhancing Diverse Perspectives (PEDP) to foster inclusivity among diverse teams and institutions. The initiative anticipates awarding approximately $10 million across 15-20 projects, with applications due by January 20, 2026. For further details, interested applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-017.html.