Impact of Comorbidities and Co-Infections on HIV Reservoirs (R01 Clinical Trial Not Allowed)

Active
Yes
Status
Posted
Published Date
February 29th, 2024
Close Date
July 30th, 2024
Opportunity No.
RFA-DK-25-013

Agency

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Summary

The National Institutes of Health (NIH) has posted a grant opportunity titled "Impact of Comorbidities and Co-Infections on HIV Reservoirs (R01 Clinical Trial Not Allowed)". This grant aims to foster new multi-disciplinary teams to investigate how HIV comorbidities and co-infections interact with viral reservoirs, potentially affecting cure strategies. The teams will study the impact of inflammation, metabolic perturbations, and other pathophysiological processes associated with these conditions on reservoir dynamics, as well as the interplay between these conditions and co-infections on HIV reservoir biology. The grant does not require cost sharing or matching. The eligible applicants include various institutions and organizations, such as Alaska Native and Native Hawaiian Serving Institutions, Faith-based or Community-based Organizations, and U.S. Territories or Possessions. The grant opportunity will close on July 30, 2024, and more information can be found at the following link: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-25-013.html. For any inquiries, please contact NIH Grants Information at grantsinfo@nih.gov.

Description

This Notice of Funding Opportunity (NOFO) seeks to foster new multi-disciplinary teams to address how HIV Comorbidities and co-infections within the missions of NIDDK and NIAID interact with viral reservoirs, potentially confounding cure strategies aimed at either sustained viral suppression or elimination from the body. These teams will mechanistically interrogate the impact of inflammation, metabolic perturbations, or other pathophysiological processes associated with these comorbidities or co-infections on reservoir dynamics, and/or the interplay of these conditions and co-infections on HIV reservoir biology in ways that are likely to interact with potential cure strategies.

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