The National Institutes of Health (NIH) has announced a funding opportunity titled "Tailoring HIV Curative Strategies to the Participant," aimed at developing clinical research platforms for tailored HIV curative strategies through cooperative agreements. The initiative seeks to fund 2-3 multidisciplinary projects with a total budget of $7 million for fiscal year 2025, focusing on proof-of-concept studies that target participants' unique HIV reservoirs and immunologic profiles, while avoiding clinical trial proposals. Interested applicants must propose innovative techniques for profiling these reservoirs and emphasize tailored immunologic approaches, with applications due by July 30, 2024. For further details, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-011.html.