NEI Translational Research Program for Therapeutics (R33 Clinical Trial Not Allowed)
ID: 358047Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $1M

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/358047

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-363.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering the NEI Translational Research Program for Therapeutics (Funding Opportunity Number: PAR-25-363), aimed at advancing innovative therapeutic solutions for visual system diseases. This program seeks to support multidisciplinary teams in generating preclinical data that will facilitate the development of treatments leading to FDA Investigational New Drug (IND) or Investigational Device Exemption (IDE) applications, particularly targeting significant ocular disorders such as retinal diseases and glaucoma. With a funding cap of $1 million annually for a maximum of three years, applicants must demonstrate milestone-driven progress in IND/IDE-enabling studies, with applications due by February 16, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-363-Full-Announcement.html
    PAR-25-363.html
    The Department of Health and Human Services—National Institutes of Health (NIH)—announces the NEI Translational Research Program for Therapeutics (Funding Opportunity Number: PAR-25-363), aimed at advancing innovative therapeutic solutions for visual system diseases. This program supports multidisciplinary teams in generating preclinical data conducive to developing treatments that may lead to FDA Investigational New Drug (IND) or Investigational Device Exemption (IDE) applications. The initiative targets significant ocular disorders, including retinal diseases and glaucoma, with the intent of improving the quality of life for individuals affected by vision impairments. Funding is capped at $1 million annually for a maximum of three years, emphasizing milestone-driven progress in IND/IDE-enabling studies. Key dates include the application due date of February 16, 2025, with a focus on the necessity for FDA pre-submission meeting evidence. Applications must encompass detailed project management strategies, with defined milestones and specific criteria to gauge progress. Non-responsiveness criteria include failure to align with NEI strategic goals and absence of defined R33 milestones. Emphasizing innovation, rigor, and feasibility, the review process will prioritize applications that offer substantial scientific merit. This initiative underscores NIH's commitment to accelerating advancements in eye and vision research for clinician application.
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