The National Institutes of Health (NIH) is offering a funding opportunity through the NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed). This grant aims to support meritorious research projects that utilize existing databases for secondary data analyses related to vision health, with a focus on enhancing statistical methodologies for analyzing vision data. The initiative is crucial for addressing major causes of blindness and improving the understanding of visual system development and function. Eligible applicants include a wide range of institutions, and the total project budget can reach up to $275,000 over two years. Interested parties should submit their applications by October 16, 2027, and can find more information by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-357.html.