The National Eye Institute (NEI) is offering funding opportunities for Collaborative Clinical Vision Research Projects through a Coordinating Center grant (UG1 Clinical Trial Required). The grant aims to support large-scale clinical trials focused on evaluating interventions for vision disorders. Key responsibilities of the Coordinating Center include providing scientific and technical leadership, managing trial data and safety oversight, and collaborating with various research centers. Applications for this competitive grant must adhere to strict guidelines and demonstrate the project's significance, innovation, and the capabilities of the Principal Investigators. Various types of institutions, including higher education and nonprofit organizations, are encouraged to apply. The optimal project duration is up to five years, and while there is no explicit budget cap, applications must accurately reflect project needs. This funding initiative emphasizes the NEI's commitment to advancing vision research and improving public health outcomes related to vision disorders.