The National Institutes of Health (NIH) plans to publish a Notice of Funding Opportunity (NOFO) for the development, characterization, and advancement of gene- and cell-based approaches to achieve long-term remission or elimination of HIV. This NOFO, expected to be published in April 2024, aims to solicit applications for cell and gene therapies for HIV cure. The NIH is seeking meaningful collaborations, interdisciplinary teams, and responsive applications. The NOFO will utilize the P01 (Research Program Projects) activity code. The estimated total program funding is $13,500,000, with an award ceiling of $2,200,000. It is anticipated that three awards will be granted. The application due date is expected to be in July 2024. The estimated award date and project start date are both set for March 2025.