The National Institutes of Health (NIH) is planning to publish a Notice of Funding Opportunity Announcement (NOFO) for the Complement-ARIE New Approach Methodologies (NAMs) Data Hub and Coordinating Center, which will be available under the U24 activity code. This initiative aims to support the Complement Animal Research In Experimentation (Complement-ARIE) program, encouraging the research community to form collaborations and develop responsive projects. The funding opportunity is significant for advancing health-related research methodologies, with an estimated total program funding of $5 million and a single award anticipated. Interested applicants should note that the synopsis is expected to be posted on November 29, 2024, with a closing date of March 10, 2025, and an estimated award date of December 1, 2025.