The National Institutes of Health (NIH) is forecasting a funding opportunity announcement for the establishment of Diagnostic Centers of Excellence (DCoE) as part of the Undiagnosed Diseases Network (UDN). The objective is to solicit proposals from qualified clinical sites across the U.S. to provide expert diagnostic services for patients with challenging undiagnosed diseases, leveraging data management and clinical research support from a Data Management and Coordinating Center (DMCC). This initiative aims to enhance the diagnostic journey for patients and promote scientific discovery through collaboration and data sharing. Interested applicants can expect the program announcement to be published in spring 2023, with an application due date in early summer 2023. For further inquiries, contact Argenia Doss, PhD, at argenia.doss@nih.gov or call 301-827-1373.