The National Institutes of Health (NIH) plans to publish a Notice of Funding Opportunity (NOFO) for the Intellectual and Developmental Disabilities Research Centers (IDDRCs) in 2025, with an emphasis on advancing research related to intellectual and developmental disabilities (IDD). This initiative aims to foster collaborative research efforts across basic, translational, and clinical domains to enhance the diagnosis, prevention, treatment, and amelioration of IDD. The funding opportunity, utilizing the P50 activity code, will support multi-project grant awards with an award ceiling of $1 million, and the NOFO is expected to be published in Summer 2024, with applications due in Fall 2024. Interested applicants should prepare for the anticipated timeline, as the estimated project start date is July 1, 2025.