The National Institutes of Health (NIH) is offering a funding opportunity titled "Limited Competition: Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2)," aimed at enhancing the capabilities of existing COBRE Phase 1 centers over a five-year period. Eligible applicants must hold an active COBRE Phase 1 award and demonstrate how previous funding has contributed to research success and institutional improvements, with a structured application that includes an Administrative Core, 2-5 Research Projects, and optional Research Cores. This initiative is crucial for fostering sustainable biomedical research centers at Institutional Development Award (IDeA)-eligible institutions, promoting diversity and collaboration among research teams. The program has an annual budget ceiling of $1.5 million, with applications due by May 28, 2025. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the full announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-23-063.html.