The National Institutes of Health (NIH) is inviting applications for the Leadership and Coordination Center (LACC) to renew the MACS/WIHS Combined Cohort Study (MWCCS), focusing on the health and survival of middle-aged and older adults living with HIV in the United States. This six-year initiative, running from 2026 to 2032, aims to follow approximately 5,600 participants using a populomics approach to assess various health determinants, thereby enhancing clinical guidance, operational accountability, and community engagement across multiple study components. The LACC will play a crucial role in addressing health disparities related to HIV, particularly as aging populations face increasing comorbidities, with an estimated total program funding of $2 million available for this opportunity. Applications are due by May 2, 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.