The National Institutes of Health (NIH) is offering a funding opportunity titled "Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)" aimed at enhancing research on the intersection of HIV and aging. The program seeks applications that focus on improving the understanding of biological, clinical, and socio-behavioral aspects of aging in the context of HIV infection, as well as developing better methods for testing, preventing, and managing HIV-related health issues among older populations. This initiative is particularly significant given the projected increase in the prevalence of HIV among older adults, which is expected to rise from 53% to over 70% by 2030, highlighting the urgent need to address the complex challenges associated with aging and HIV. Interested applicants can submit proposals until January 7, 2027, with no budget limits as long as they align with project needs; for further inquiries, contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-25-354.html.