Discovery and Development of Natural Products for Cancer Interception and Prevention (UG3/UH3 Clinical Trial Not Allowed)
ID: 347073Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $250K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/347073

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-23-028.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Discovery and Development of Natural Products for Cancer Interception and Prevention" (RFA-CA-23-028), aimed at supporting the identification and development of novel natural products that are safe and effective for cancer prevention. This initiative utilizes a phased cooperative agreement mechanism (UG3/UH3) to facilitate the discovery of non-toxic cancer preventive agents, leveraging the NIH's extensive natural product library of approximately 500,000 samples. Eligible applicants, including higher education institutions, non-profits, and government agencies, can receive funding of up to $250,000 per year for the UG3 phase and $400,000 per year for the UH3 phase, with a total funding period of up to five years. Interested parties should submit their applications by June 13, 2025, and can direct inquiries to grantsinfo@nih.gov for further information.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-CA-23-028-Full-Announcement.html
    RFA-CA-23-028.html
    The National Cancer Institute (NCI) has announced a funding opportunity (RFA-CA-23-028) to support the identification and development of natural products for cancer interception and prevention through a phased cooperative agreement mechanism (UG3/UH3). The initiative aims to discover novel, safe, and effective cancer preventive agents derived from natural products, leveraging the NCI's extensive pre-fractionated natural product library of approximately 500,000 samples. The UG3 phase allows for up to three years of funding to establish milestones for initial target selection, assay development, and screening of natural agents. A successful progression to the UH3 phase will enable larger scale evaluation of selected compounds for pharmacokinetics and efficacy testing over two additional years. Eligible applicants include higher education institutions, non-profits, and government agencies, with maximum funding of $250,000/year for UG3 projects and $400,000/year for UH3 projects, totaling up to five years of support. Applications must adhere to strict guidelines and outline their research strategies, with a defined milestone plan necessary for advancement from the UG3 to the UH3 phase. This funding opportunity emphasizes the discovery of non-toxic natural agents, with a focus on their clinical relevance to public health through efficient cancer prevention strategies.
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