The Department of Health and Human Services, through the Agency for Healthcare Research and Quality (AHRQ), has announced funding for the "AHRQ Small Research Projects to Advance the Science of Primary Care" (R03 program). This funding opportunity aims to support small-scale primary care research projects that can yield impactful results with limited resources and within a short timeframe, specifically targeting areas such as quality, accessibility, and health equity in primary care. Applicants can seek up to $100,000 in funding for projects lasting up to two years, with a focus on addressing significant challenges in primary care delivery, particularly for disadvantaged populations and those with multiple chronic conditions. Funding is contingent upon available resources and successful applications. The NOFO encourages diverse organizations, particularly higher education institutions and nonprofits, to apply, and emphasizes the importance of including health equity considerations in proposed research. The application process requires careful adherence to guidelines and submission through designated platforms. Applications will be reviewed based on significance, investigator credentials, innovation, approach, and environment. Successful projects are expected to report on their performance in enhancing primary care science, benefiting the healthcare system at large.