The U.S. Agency for International Development (USAID) is offering a funding opportunity for the "HIV Prevention Among Adolescent Girls and Young Women and Other Vulnerable Youth Populations - DREAMS South" program, aimed at significantly reducing new HIV infections among youth aged 10-24 in high-incidence areas of South Africa. The initiative seeks to enhance community leadership, improve access to biomedical HIV services, and provide technical assistance to government departments, with a focus on community-driven solutions and the involvement of youth in prevention efforts. This program is critical for addressing the socio-economic determinants of HIV risk and promoting gender equity, with an estimated budget of $52 million to $58 million over five years. Interested local entities must submit their applications by February 18, 2025, and can direct inquiries to Alejandra Garcia at pretoriaapplications@usaid.gov.