Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)
ID: 356801Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $750K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356801

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-058.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering the Innovation Grants to Nurture Initial Translational Efforts (IGNITE) funding opportunity, aimed at supporting pharmacodynamic, pharmacokinetic, and in vivo efficacy studies of therapeutic agents for neurological and neuromuscular disorders. This grant follows the R61/R33 phased award mechanism, where the R61 phase focuses on preparation and characterization, while the R33 phase emphasizes efficacy studies, with a critical transition contingent upon meeting specific milestones. The program encourages collaboration among various organizations, including nonprofit entities and academic institutions, to accelerate the development of promising therapies, with awards capped at $750,000 over a maximum project duration of three years. Interested applicants can find more information and application instructions at the NIH grants website, and the deadline for submissions is October 20, 2027.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-058.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), announces the Innovation Grants to Nurture Initial Translational Efforts (IGNITE) funding opportunity (PAR-25-058). This grant aims to support pharmacodynamic, pharmacokinetic, and in vivo efficacy studies of therapeutic agents for neurological disorders. The application follows the R61/R33 phased award mechanism, with the R61 phase focusing on preparation and characterization, and the R33 phase emphasizing efficacy studies. A critical transition from R61 to R33 is contingent upon meeting specific milestones, emphasizing scientific rigor and transparency. Eligibility is open to various organizations, including nonprofit entities and academic institutions, with a total project duration not exceeding three years. Awards are capped at $499,000 per year, with cumulative costs limited to $750,000. The program promotes collaboration, encouraging applicants to connect with industry experts and technology transfer officials. The NIH underscores the importance of innovative approaches and robust experimental data while implementing NIH data sharing policies. The announcement details application instructions, review criteria, and additional requirements to ensure a transparent, rigorous funding process. This funding opportunity is crucial for accelerating the development of promising therapies that enhance treatment options for neurological and neuromuscular disorders.
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