The National Institutes of Health (NIH) is offering Exploratory Grants in Cancer Control (R21 Clinical Trial Optional) to support innovative research aimed at enhancing cancer control through behavioral modification, screening, and understanding the etiological factors of cancer. This funding opportunity encourages the submission of exploratory and developmental research grant applications that can significantly advance population-based cancer research, with a maximum budget of $275,000 available for a two-year project period, without the need for extensive preliminary data. The initiative emphasizes the importance of addressing public health challenges related to cancer epidemiology and health disparities, particularly encouraging participation from underrepresented groups in research. Applications are due by 5 PM local time on October 8, 2024, and interested applicants can find more information and guidelines at the NIH website or contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov.