The National Institutes of Health (NIH) announces an Exploratory Grant Award (R21) aimed at promoting workforce diversity in basic cancer research. This funding opportunity seeks to support New Investigators and Early Stage Investigators from underrepresented backgrounds in developing innovative cancer research studies. The initiative is a reissue of a previous program, continuing the NIH's effort to diversify biomedical research and enhance the research capabilities available to address health disparities. Applications are open for new, renewal, or resubmission proposals, with a total award budget not exceeding $275,000 for a maximum period of two years. The focus is on basic cancer biology research, particularly that which addresses cancer health disparities among racial and ethnic minorities. All applicants must comply with specific guidelines and submissions are reviewed based on scientific merit and innovation. The NIH underscores the importance of a diverse research workforce and expects this program to uplift talented researchers, ultimately advancing knowledge in cancer research and benefiting all segments of society. The application process is detailed, emphasizing the necessity of following NIH's application instructions strictly. Consequently, the program aims to foster a scientific community that contains varied perspectives and experiences, which is essential for tackling complex scientific questions effectively.