Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
ID: 342124Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/342124

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-22-192.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity for the establishment of a Clinical Coordinating Center (CCC) to lead multi-site investigator-initiated clinical trials relevant to the National Heart, Lung, and Blood Institute (NHLBI). The objective of this cooperative agreement is to develop and implement a comprehensive scientific and operational plan for clinical trials, which must include strategies for community engagement and efforts to address health disparities. This initiative emphasizes the importance of innovative research designs and methodologies in tackling significant health issues, with applications due by September 11, 2025. Interested applicants can find more information and guidelines at the NIH website or contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov for further inquiries.

    Point(s) of Contact
    OERWebmaster03@od.nih.gov
    Files
    Title
    Posted
    PAR-22-192-Full-Announcement.html
    PAR-22-192.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), issues a Funding Opportunity Announcement (FOA) for a Clinical Coordinating Center (CCC) to lead multi-site clinical trials in health research. This cooperative agreement mechanism aimed at investigator-initiated trials encourages innovative designs and approaches to tackle significant health issues relevant to the National Heart, Lung, and Blood Institute (NHLBI). A successful application requires a detailed scientific and operational plan that includes community engagement strategies and efforts to reduce health disparities. Applications must follow strict submission guidelines, including parallel applications for a collaborating Data Coordinating Center (DCC). Key components of the funding include a start-up phase (UG3) to develop trial protocols and a subsequent execution phase (UH3) lasting up to four years. Applicants are assessed based on significant criteria like the significance of the research question, investigator qualifications, innovation, methodological strength, engagement with diverse populations, and overall project feasibility. This initiative underscores the government’s commitment to advancing clinical research while prioritizing inclusivity and scientific excellence.
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