Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)
ID: 342125Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/342125

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-22-193.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity for a Data Coordinating Center (DCC) to support multi-site investigator-initiated clinical trials through a cooperative agreement. The DCC will be responsible for project coordination, data management, and biostatistical support, collaborating closely with a Clinical Coordinating Center (CCC) to enhance community engagement and diversity in clinical trial recruitment. This initiative is crucial for advancing research in therapeutic and preventive strategies, particularly in addressing health disparities through diverse clinical trial participation. Interested applicants must submit their proposals by September 11, 2025, and can find additional information and guidelines at the NIH website or contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov.

    Point(s) of Contact
    OERWebmaster03@od.nih.gov
    Files
    Title
    Posted
    PAR-22-193-Full-Announcement.html
    PAR-22-193.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is offering a funding opportunity for a Data Coordinating Center (DCC) for multi-site investigator-initiated clinical trials. This initiative aims to support clinical trials aimed at assessing the efficacy of therapeutic and preventive strategies, with specific encouragement for innovative trial designs. The DCC will collaborate with a Clinical Coordinating Center (CCC) and is required to manage project coordination, data management, and biostatistical support, demonstrating effective collaboration with the CCC to enhance community engagement and diversity in clinical trial recruitment. Key dates indicate the open application period from September 11, 2022, until September 12, 2025. Eligible applicants include a diverse range of organizations such as higher education institutions, nonprofits, governments, and foreign institutions. Applications must comply with NIH guidelines, including performance-driven milestones, participant safety, and the inclusion of underrepresented populations in clinical research. Successful applicants will demonstrate effective project management capabilities, innovative approaches to trial design, and compliance with funding policies. This funding opportunity emphasizes NIH's commitment to diversity within the research workforce and the necessity for diverse clinical trial participation to address health disparities.
    Similar Opportunities
    Data Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative U24 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Center for Complementary and Integrative Health (NCCIH), is inviting applications for a Data Coordinating Center (DCC) to support multi-site, investigator-initiated clinical trials focused on mind and body interventions. The DCC will be responsible for project coordination, administrative support, data management, and biostatistical analysis for Phase III clinical trials, and must be submitted alongside a Clinical Coordinating Center (CCC) proposal. This initiative is crucial for advancing research in complementary and integrative health strategies that address public health challenges, emphasizing participant diversity and data integrity. Interested applicants should note that the application deadline is January 20, 2025, with a funding period of up to 7 years, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Natural Product Multi-Site Clinical Trial Data Coordinating Center (Collaborative U24 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for the Natural Product Multi-Site Clinical Trial Data Coordinating Center (DCC) through a cooperative agreement mechanism. This initiative invites applications for a DCC that will collaborate with a Clinical Coordinating Center (CCC) to conduct multi-site clinical trials focused on the efficacy and effectiveness of natural products, requiring simultaneous submission of both applications. The program emphasizes the importance of maintaining data integrity, promoting diversity in participant recruitment, and achieving specific milestones for continued funding, while also necessitating a Plan for Enhancing Diverse Perspectives (PEDP) to ensure inclusivity in research. Interested applicants can find more information and application details on the NIH grants website, with a submission deadline of July 14, 2026, and a contact email for inquiries at grantsinfo@nih.gov.
    Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a Notice of Funding Opportunity (NOFO) for the establishment of a Clinical Coordinating Center (CCC) to support multi-site investigator-initiated clinical trials under the UG3/UH3 cooperative agreement mechanism. This initiative aims to facilitate trials focused on efficacy, comparative effectiveness, and implementation research, particularly those that address health disparities and promote community engagement. Eligible applicants include a diverse range of organizations, such as academic institutions, nonprofit entities, and tribal governments, with applications required to detail project management, participant recruitment strategies, and a Plan for Enhancing Diverse Perspectives (PEDP). The application period opens on January 11, 2025, with a submission deadline of September 11, 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for the development of a Clinical Coordinating Center (CCC) to support multi-site investigator-initiated clinical trials under the UG3/UH3 activity codes. This initiative aims to foster innovative trial designs relevant to the National Heart, Lung, and Blood Institute's (NHLBI) research mission, requiring comprehensive project plans that address participant recruitment, milestone achievements, and strategies for enhancing community engagement and diversity. The funding mechanism is bi-phasic and necessitates simultaneous applications for both a CCC and a collaborating Data Coordinating Center (DCC), emphasizing strong project management and a commitment to minimizing health disparities. Interested applicants must submit their proposals by September 11, 2025, and can reach out to the NIH OER Webmaster at OERWebmaster03@od.nih.gov for further inquiries. More details can be found in the full announcement at http://grants.nih.gov/grants/guide/pa-files/PAR-22-192.html.
    Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for cooperative agreements to establish a Clinical Coordinating Center (CCC) for multi-site, investigator-initiated clinical trials focused on the effects of natural products, such as botanicals and dietary supplements. Applicants are required to develop a comprehensive scientific and operational plan for the clinical trial, including project management, participant recruitment, and performance milestones, while also submitting a companion Data Coordinating Center (DCC) application. This initiative aims to generate robust clinical data to inform integrative health approaches and public health strategies, with applications opening on January 20, 2025, and closing on July 14, 2026. For further details, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-24-312.html.
    Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for the establishment of a Clinical Coordinating Center (CCC) to support multi-site investigator-initiated clinical trials focused on natural products, such as botanicals and dietary supplements. Applicants are required to submit a comprehensive plan detailing project management, participant recruitment, and clinical trial execution, while also ensuring alignment with NIH standards. This initiative emphasizes the importance of evidence-based research in natural products and mandates the submission of a corresponding Data Coordinating Center (DCC) proposal to oversee data management and analysis. Interested applicants should note that the application deadline is July 15, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. For additional details, applicants can refer to the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-24-123.html.
    Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative UG3/UH3 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Center for Complementary and Integrative Health (NCCIH), is offering a funding opportunity for the establishment of a Clinical Coordinating Center (CCC) to support multi-site investigator-initiated clinical trials focused on mind and body interventions. Applicants are required to develop comprehensive plans that include project management, participant recruitment, and data analysis, while collaborating with a corresponding Data Coordinating Center (DCC) to ensure the trials are scientifically robust and aligned with NCCIH's research priorities. This initiative aims to explore the efficacy and effectiveness of complementary health approaches, emphasizing the inclusion of diverse populations and the necessity for a detailed plan to enhance diversity in research teams and subjects. Interested applicants must submit their proposals by January 20, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. For more details, please refer to the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-24-275.html.
    Notice of Intent to Publish a Funding Opportunity Announcement for Data Management and Coordinating Center (DMCC) for Rare Diseases Clinical Research Network (RDCRN) (U2C Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) plans to publish a Funding Opportunity Announcement (FOA) for the establishment of a Data Management and Coordinating Center (DMCC) as part of the Rare Diseases Clinical Research Network (RDCRN). This initiative aims to enhance the diagnosis, management, and treatment of rare diseases by facilitating collaborative, multi-site, patient-centric research through the RDCRN and supporting the activities of the Rare Diseases Clinical Research Consortia (RDCRC). The estimated total program funding for this grant is $1,000,000, with the FOA expected to be published in 2024 and awards anticipated in 2025. Interested applicants can reach out to Dr. Tiina K. Urv at urvtiin@mail.nih.gov or by phone at 301-827-2746 for further information.
    Limited Competition: NCI National Clinical Trials Network - Network Group Statistics and Data Management Centers (U10 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for the Limited Competition: NCI National Clinical Trials Network - Network Group Statistics and Data Management Centers (U10 Clinical Trial Required). This initiative invites applications primarily from current award recipients under RFA-CA-17-057 to sustain Statistics and Data Management Centers (SDMCs) for the NCI National Clinical Trials Network (NCTN), which focuses on advancing cancer treatment through multi-center clinical trials, particularly late-phase trials and biomarker-driven therapies. The funding, totaling approximately $47 million, aims to support five awards over a project period of up to six years, emphasizing the need for substantial Federal scientific involvement and robust statistical analysis plans. Interested applicants must submit their proposals by January 24, 2025, and can direct inquiries to grantsinfo@nih.gov for further information.
    Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed)" aimed at enhancing resources for investigating undiagnosed diseases through a network of clinical sites. This initiative seeks to designate successful applicants as Diagnostic Centers of Excellence (DCoE), which will be responsible for generating clinical data to be shared with the Data Management Coordinating Center (DMCC), thereby promoting collaboration among clinicians and researchers to improve diagnostic capabilities, particularly for health disparity populations. The program does not provide direct budgetary support but allows successful applicants to apply for subawards for research activities, with applications open from April 15, 2023, until the final deadline of May 15, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.