Single Source: Bench to Bassinet Congenital Heart disease Advancing New understanding in GEnomics Cohort (B2B CHANGE Cohort) Data Coordinating Center (U01 Clinical Trial Not Allowed)
ID: 358120Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $4M

Eligible Applicants

Public and State Controlled Institutions of Higher Education

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/358120

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-007.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity for a single-source cooperative agreement aimed at establishing the B2B CHANGE Cohort Data Coordinating Center, transitioning from the existing Bench-to-Bassinet (B2B) Program. This initiative, primarily awarded to Cincinnati Children's Hospital Medical Center, focuses on advancing the understanding of congenital heart disease (CHD) through the analysis of genomic and clinical data from over 13,000 individuals, with an emphasis on deep phenotyping and longitudinal studies to improve clinical outcomes. The project aims to enhance community engagement, ensure data availability for the scientific community, and promote diversity in research participation, with a mandatory Plan for Enhancing Diverse Perspectives (PEDP) required from applicants. Interested parties should note that the funding ceiling is set at $4,010,000, with applications due by March 18, 2025. For further inquiries, contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-HL-26-007-Full-Announcement.html
    RFA-HL-26-007.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), has released a funding opportunity announcement for a single-source cooperative agreement aimed at transitioning the Bench-to-Bassinet (B2B) Program Coordinating Center into a Congenital Heart disease Advancing New understanding in GEnomics (B2B CHANGE) Cohort Data Coordinating Center (CC). This initiative, primarily awarded to Cincinnati Children's Hospital Medical Center, seeks to enhance the understanding of congenital heart disease (CHD) by leveraging existing genomic and clinical data from over 13,000 individuals, with the goal of improving clinical outcomes through deep phenotyping and longitudinal studies. Funding will enable logistical support, community engagement, and the establishment of a diverse cohort for clinical follow-ups. Key components of the project include ensuring data availability to the broader scientific community, enhancing diversity in research participation, and promoting collaborative research efforts. The project outlines milestones for recruitment, data collection, and sharing resources via public databases. A Plan for Enhancing Diverse Perspectives (PEDP) is mandatory for applicants, reflecting NIH's commitment to inclusivity in research. Overall, this funding opportunity is a strategic effort to strengthen CHD research through data-driven insights and comprehensive participant engagement.
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