BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)
ID: 352511Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) is offering a Notice of Funding Opportunity (NOFO) aimed at developing production and distribution facilities for brain cell type-specific access reagents as part of the BRAIN Initiative. This initiative seeks to enhance neurotechnologies that improve the understanding of brain function and the development of treatments for brain disorders, with a focus on scaling up the production of specific reagents such as viral vectors and nucleic acid constructs. Successful applicants will be required to collaborate with Research Resource for Design and Development (RRDD) projects, execute scaled production, and ensure broad dissemination of these reagents while promoting diversity within research teams through a Plan for Enhancing Diverse Perspectives (PEDP). The anticipated funding is approximately $2.4 million per year to support 2 to 4 awards, with a maximum project period of 5 years. Interested parties can find more information and contact NIH Grants Information at grantsinfo@nih.gov, with applications due by July 1, 2026.

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    Title
    Posted
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is issuing a Notice of Funding Opportunity (NOFO) aimed at developing production and distribution facilities for brain cell type-specific access reagents as part of the BRAIN Initiative. The initiative focuses on advancing neurotechnologies to enhance understanding of brain function and the development of treatments for brain disorders. The funding opportunity (RFA-MH-25-105) seeks applications to scale up the production of specific reagents—like viral vectors and nucleic acid constructs—that facilitate detailed studies of neural circuits. Successful applicants must interface with Research Resource for Design and Development (RRDD) projects, execute scaled production, disseminate reagents broadly, and coordinate data management. An emphasis is placed on diversity and inclusivity within research teams; applicants are required to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposal. The anticipated funding is estimated at $2.4 million per year to support 2 to 4 awards, with an application maximum project period of 5 years. The NOFO aims to foster collaboration across institutions and disciplines to enrich neuroscience research through the broad availability of these specialized reagents.
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