The National Institutes of Health (NIH) has announced a Notice of Funding Opportunity (NOFO) titled "Development and Validation of Human Cellular Models for Alzheimer's Disease-Related Dementias (ADRD)," aimed at enhancing research through the creation of complex human cellular models. This initiative seeks to support the development and validation of novel cellular systems that accurately replicate the multifaceted pathologies associated with ADRD, with a focus on models that demonstrate face and construct validity. The funding opportunity, totaling up to $4.5 million for FY2025, is intended to support up to six grants and aligns with the National Plan to Address Alzheimer's Disease, emphasizing the importance of innovative research in understanding neurodegenerative dementias. Interested applicants must submit their proposals by October 21, 2024, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. More details can be found at the provided link: https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-032.html.