Development and Validation of Human Cellular Models for Alzheimer's Disease-Related Dementias (ADRD) (R01 - Clinical Trial Not Allowed)
ID: 352495Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $500K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/352495

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-032.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a Notice of Funding Opportunity (NOFO) titled "Development and Validation of Human Cellular Models for Alzheimer's Disease-Related Dementias (ADRD)," aimed at enhancing research through the creation of complex human cellular models. This initiative seeks to support the development and validation of novel cellular systems that accurately replicate the multifaceted pathologies associated with ADRD, with a focus on models that demonstrate face and construct validity. The funding opportunity, totaling up to $4.5 million for FY2025, is intended to support up to six grants and aligns with the National Plan to Address Alzheimer's Disease, emphasizing the importance of innovative research in understanding neurodegenerative dementias. Interested applicants must submit their proposals by October 21, 2024, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. More details can be found at the provided link: https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-032.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-NS-24-032-Full-Announcement.html
    RFA-NS-24-032.html
    The Department of Health and Human Services has issued a Notice of Funding Opportunity (NOFO) titled "Development and Validation of Human Cellular Models for Alzheimer's Disease-Related Dementias (ADRD)" to enhance research on ADRD through the creation of complex human cellular models. The funding, totaling up to $4.5 million for FY2025, aims to support up to six grants and focuses on developing cellular systems that replicate multiple human disease aspects relevant to ADRD. The initiative aligns with the National Plan to Address Alzheimer's Disease and responds to priorities from recent research summits. Key application dates include a submission deadline of October 22, 2024, with proposals required to demonstrate both face and construct validity. Only applications within the NINDS's mission and focused on human cellular models are eligible, excluding those that involve animal models, simple cultures, or develop models without validation. The NOFO encourages collaboration and recommends leveraging existing resources. Complete registration with necessary platforms is required before submission. The evaluation will prioritize scientific merit, impact, and the appropriateness of the model to human ADRD, ensuring a rigorous, unbiased approach is maintained throughout the research process.
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