The National Institutes of Health (NIH) has posted a grant opportunity titled "Development and Validation of Human Cellular Models for Alzheimer's Disease-Related Dementias (ADRD) (R01 - Clinical Trial Not Allowed)". This grant aims to support the development and validation of novel human cellular models that are clinically and/or pathophysiologically relevant to ADRD. These cellular models should capture the various pathologies and multiple cell types observed in ADRDs. The validation process should include internal, face, construct, and predictive validation to the extent possible. The goal of these models is to aid in therapy development and enhance our understanding of human disease mechanisms and predisposition to developing neurodegenerative dementias. The models should be novel, complex, and address existing gaps in currently available models. Multidisciplinary teams are highly encouraged, and leveraging existing NIH cell repository resources is also encouraged. The grant has a funding ceiling of $500,000 and does not require cost sharing or matching. The deadline for applications is October 21, 2024. For more information and to apply, visit the following link: http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-032.html. For any inquiries, contact NIH Grants Information at grantsinfo@nih.gov.